open access

Vol 14, No 1-2 (2012)
Original articles
Published online: 2012-11-19
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Variability of platelet aggregation in patients with critical limb ischaemia during 6 months of dual anti-platetlet therapy

Grzegorz Biolik, Damian Ziaja, Tomasz Urbanek, Wacław Kuczmik, Teresa Twardela, Krzysztof Ziaja
Chirurgia Polska 2012;14(1-2):30-35.

open access

Vol 14, No 1-2 (2012)
Original articles
Published online: 2012-11-19

Abstract

There was present an analysis of platelet variances in responsibility for dual-antiplatelet therapy — acetylsalicylic acid and clopidogrel — in patients with IV stage of limb ischaemia in long term follow-up. This is a pioneer paper and it is focused on the following weakenees effect of antiplatelet drugs in long time period despite of the blockade of IIbIIIa platelet receptor expression and blockage of thromboxane pathway.

Abstract

There was present an analysis of platelet variances in responsibility for dual-antiplatelet therapy — acetylsalicylic acid and clopidogrel — in patients with IV stage of limb ischaemia in long term follow-up. This is a pioneer paper and it is focused on the following weakenees effect of antiplatelet drugs in long time period despite of the blockade of IIbIIIa platelet receptor expression and blockage of thromboxane pathway.
Get Citation

Keywords

critical limb ischaemia; peripherial arterial occlusive disease; trophic changes; impedance aggregometry; platelet hyper-reactivity; limb amputation; dual antiplatelet therapy; acetylsalicylic acid; clopidogrel; statins; LMWH; reconstructive procedur

About this article
Title

Variability of platelet aggregation in patients with critical limb ischaemia during 6 months of dual anti-platetlet therapy

Journal

Chirurgia Polska (Polish Surgery)

Issue

Vol 14, No 1-2 (2012)

Pages

30-35

Published online

2012-11-19

Bibliographic record

Chirurgia Polska 2012;14(1-2):30-35.

Keywords

critical limb ischaemia
peripherial arterial occlusive disease
trophic changes
impedance aggregometry
platelet hyper-reactivity
limb amputation
dual antiplatelet therapy
acetylsalicylic acid
clopidogrel
statins
LMWH
reconstructive procedur

Authors

Grzegorz Biolik
Damian Ziaja
Tomasz Urbanek
Wacław Kuczmik
Teresa Twardela
Krzysztof Ziaja

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