English Polski
Vol 25, No 1-2 (2023)
Research paper
Published online: 2024-09-13

open access

Page views 45
Article views/downloads 23
Get Citation

Connect on Social Media

Connect on Social Media

Vascular reconstructive surgery in patients with popliteal artery aneurysm — an analysisof the predictive factors of the successful revascularisation

Dariusz Mościcki1, Tomasz Urbanek2, Wacław Kuczmik2, Krzysztof Ziaja2
DOI: 10.5603/chp.101519
Chirurgia Polska 2023;25(1-2):1-16.

Abstract

Introduction: Popliteal artery aneurysm (PPA) belongs to the most commonly recognized peripheral
artery aneurysms. The presence of PPA complications especially the presence of PPA related acute leg
ischemia significantly increase the risk of leg amputation. In the study, the population of the elective and
emergency patients with PPA treated in the Department of General Surgery, Vascular Surgery, Angiology
and Phlebology of the Medical University of Silesia was analyzed. In the study protocol the primary and
secondary patency as well as the predictive factors for the PAA revascularization success were evaluated
in the patients with and without acute leg ischemia due to PAA.

Material and methods: 97 patients with PAA were recruited into the study including 38 patients with acute
leg ischemia (ALI). In both groups (elective and ALI) the surgical procedures related to the anatomy and
extend of PAA were performed. In the elective group in 66.1% of the cases posterior (prosthesis or vein
interposition) and in 33.9% medial approach (saphenous vein or prosthetic by pass implantation) was
used. In the ALI 57% of the patients underwent PAA surgery from the posterior approach and in 41%
the medial approach was used. In the ALI patients the following stages of the ischemia according to the
SVS classification were recognized: stage I — 21.2%, stage IIa — 65.6%, stage IIb 13.3%. In 5 patients
from this group preoperative thrombolytic treatment was performed. In the elective PAA group in 67%
of the patients intermittent claudication was noticed and in 5% critical leg ischemia was recognized. The
patients were followed 36 months and in the evaluation the patency of the reconstruction, amputation
rate as well as potential factors influencing on the reconstruction success, including run off vessel status
(assessed by run off score) were taken into account.

Results: In the elective group in the 3 year follow up 2 amputations were performed. 3 patients from this
group (5.1%) died. In the ALI group, 9 amputations (23.7%), including 4 early amputation — 10.5% in
the early postoperative period) as well as 3 deaths (7.9%) were noticed. The patency of the performed
reconstructions was significantly better in the group of the elective reconstructions — 3 years secondary
patency in this group was 61% (vs 31,5% in the ALI patients. In both groups, the significantly better results
were achieved when using autologous material (saphenous vein) with no result difference related to the
type of performed procedure (interposition from posterior approach vs by pass procedure) in the early
period as well as in the long term follow up. The poor run off status of the below the knee arteries had the
significant impact on the long term patency in the elective group as well as on the early reconstruction
thrombosis and leg amputation in the ALI group. In the patients with the higher advancement of the leg
ischemia, both chronic and acute, the significantly worse patency rate in the late follow up was noticed.
Among the other identified factors influencing on the long term results, the advanced age in the elective
and thrombotic occlusion of the popliteal artery in the ALI group were noticed.

Conclusions: PAA related acute leg ischemia significantly increases the risk of the early amputation rate. In
the planning of the treatment procedure in the patients with PAA and ALI, the use of the autologous material
as well as the proper run off vessel assessment and, if needed, run off vessel patency restoration should
be taken into consideration. In contrary to ALI patients, in the elective PAA treatment the run off vessel
score assessment, the stage of the leg ischemia as well as the presence of the possible popliteal artery
occlusion have limited value in the direct prediction of the early revascularization results. Independently
from the type of the reconstruction, in both groups, elective and ALI, the optimal results can be achieved
when using the revascularization based on the own saphenous vein implementation.

Article available in PDF format

View PDF (Polish) Download PDF file

References

  1. Duffy ST, Colgan MP, Sultan S, et al. Popliteal aneurysms: a 10-year experience. Eur J Vasc Endovasc Surg. 1998; 16(3): 218–222.
  2. Harder Y, Notter H, Nussbaumer P, et al. Popliteal aneurysm: diagnostic workup and results of surgical treatment. World J Surg. 2003; 27(7): 788–792.
  3. Rojas-Reyna GA, Cervantes-Castro J, Alvarado-Bachmann R, et al. Popliteal artery aneurysms. Thirty-year experience at the ABC Medical Center. Cir Cir. 2008; 76(1): 55–59.
  4. Edwards AG, Baker AR, Mitchell DC. Ligation and Bypass of Popliteal Aneurysms: a Rare Complication. EJVES Extra. 2002; 3(2): 31–32.
  5. Galland RB. Popliteal aneurysms: from John Hunter to the 21st century. Ann R Coll Surg Engl. 2007; 89(5): 466–471.
  6. Galland RB. Popliteal aneurysms: controversies in their management. Am J Surg. 2005; 190(2): 314–318.
  7. Huang Y, Gloviczki P, Noel AA, et al. Early complications and long-term outcome after open surgical treatment of popliteal artery aneurysms: is exclusion with saphenous vein bypass still the gold standard? J Vasc Surg. 2007; 45(4): 706–713; discussion 713.
  8. Ysa A, Bustabad MR, Arruabarrena A, et al. Rupture of an Infected Popliteal Aneurysm. Case Report and Review of the Literature. EJVES Extra. 2007; 14(4): 39–44.
  9. Aldoori MI, Rahman SH. Popliteal aneurysm: the need for vigilance. Age Ageing. 1999; 28(1): 5–7.
  10. Lawrence PF, Wallis C, Dobrin PB, et al. Peripheral aneurysms and arteriomegaly: is there a familial pattern? J Vasc Surg. 1998; 28(4): 599–605.
  11. Selvam A, Shetty K, James NV, et al. Giant popliteal aneurysm presenting with foot drop. J Vasc Surg. 2006; 44(4): 882–883.
  12. Loukas M, Klaassen Z, Tubbs RS, et al. Popliteal artery aneurysms: a review. Folia Morphol (Warsz). 2007; 66(4): 272–276.
  13. Lowell RC, Gloviczki P, Hallett JW, et al. Popliteal artery aneurysms: the risk of nonoperative management. Ann Vasc Surg. 1994; 8(1): 14–23.
  14. Podlaha J. Twenty years operating experience for popliteal artery aneurysm. Acta Chir Belg. 2007; 107(5): 540–543.
  15. Farber A, Angle N, Avgerinos E, et al. The Society for Vascular Surgery clinical practice guidelines on popliteal artery aneurysms. J Vasc Surg. 2022; 75(1S): 109S–120S.
  16. Mahmood A, Salaman R, Sintler M, et al. Surgery of popliteal artery aneurysms: a 12-year experience. J Vasc Surg. 2003; 37(3): 586–593.
  17. Mazzaccaro D, Carmo M, Dallatana R, et al. Comparison of posterior and medial approaches for popliteal artery aneurysms. J Vasc Surg. 2015; 62(6): 1512–1520.
  18. Huang Y, Gloviczki P, Oderich GS, et al. Outcomes of endovascular and contemporary open surgical repairs of popliteal artery aneurysm. J Vasc Surg. 2014; 60(3): 631–638.
  19. Xiao X, Feng R, Wang M, et al. Comparisons of outcomes of open surgery versus endovascular intervention for thrombotic popliteal artery aneurysm with acute lower limb ischemia: a systematic review. BMC Surg. 2022; 22: 398.
  20. Jung G, Leinweber ME, Karl T, et al. Real-world data of popliteal artery aneurysm treatment: Analysis of the POPART registry. Journal of Vascular Surgery. 2022; 75(5): 1707–1717.e2.
  21. Grip O, Mani K, Altreuther M, et al. Contemporary Treatment of Popliteal Artery Aneurysms in 14 Countries: A Vascunet Report. Eur J Vasc Endovasc Surg. 2020; 60(5): 721–729.
  22. Mandolfino T, Canciglia A, D'Alfonso M, et al. Popliteal aneurysms: comparison of the results of elective and emergent treatment. Chir Ital. 2007; 59(1): 113–116.
  23. Pulli R, Dorigo W, Castelli P, et al. A multicentric experience with open surgical repair and endovascular exclusion of popliteal artery aneurysms. Eur J Vasc Endovasc Surg. 2013; 45(4): 357–363.
  24. Kropman RHJ, Schrijver AM, Kelder JC, et al. Clinical outcome of acute leg ischaemia due to thrombosed popliteal artery aneurysm: systematic review of 895 cases. Eur J Vasc Endovasc Surg. 2010; 39(4): 452–457.
  25. Jungi S, Kuemmerli C, Kissling P, et al. Limb Salvage by Open Surgical Revascularisation in Acute Ischaemia due to Thrombosed Popliteal Artery Aneurysm. European Journal of Vascular and Endovascular Surgery. 2019; 57(3): 393–398.
  26. Ravn H, Björck M. Popliteal artery aneurysm with acute ischemia in 229 patients. Outcome after thrombolytic and surgical therapy. Eur J Vasc Endovasc Surg. 2007; 33(6): 690–695.
  27. Acosta S, Kuoppala M. Update on intra-arterial thrombolysis in patients with lower limb ischemia. J Cardiovasc Surg (Torino). 2015; 56(2): 317–324.
  28. Steinmetz E, Bouchot O, Faroy F, et al. Preoperative Intraarterial Thrombolysis before Surgical Revascularization for Popliteal Artery Aneurysm with Acute Ischemia. Ann Vasc Surg. 2000; 14(4): 360–364.
  29. Galland RB, Earnshaw JJ, Baird RN, et al. Acute limb deterioration during intra-arterial thrombolysis. Br J Surg. 1993; 80(9): 1118–1120.
  30. Grip O, Kuoppala M, Acosta S, et al. Outcome and complications after intra-arterial thrombolysis for lower limb ischaemia with or without continuous heparin infusion. Br J Surg. 2014; 101(9): 1105–1112.
  31. Gabrielli R, Rosati MS, Carra A, et al. Outcome after preoperative or intraoperative use of intra-arterial urokinase thrombolysis for acute popliteal artery thrombosis and leg ischemia. Thorac Cardiovasc Surg. 2015; 63(2): 164–167.
  32. Dragas M, Zlatanovic P, Koncar I, et al. Effect of Intra-operative Intra-arterial Thrombolysis on Long Term Clinical Outcomes in Patients with Acute Popliteal Artery Aneurysm Thrombosis. Eur J Vasc Endovasc Surg. 2020; 59(2): 255–264.
  33. Earnshaw JJ, Björck M, Jongkind V, et al. Editor's Choice - European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Acute Limb Ischaemia. Eur J Vasc Endovasc Surg. 2020; 59(2): 173–218.
  34. Farber A, Angle N, Avgerinos E, et al. The Society for Vascular Surgery clinical practice guidelines on popliteal artery aneurysms. J Vasc Surg. 2022; 75(1S): 109S–120S.
  35. Salapura V, Blinc A, Kozak M, et al. Infrapopliteal run-off and the outcome of femoropopliteal percutaneous transluminal angioplasty. Vasa. 2010; 39(2): 159–168.
  36. Rigatelli G, Zuin M, Dell'Avvocata F, et al. Impact of number of run-off vessels on interwoven nitinol mesh stents patency in the femoropopliteal segment. J Geriatr Cardiol. 2020; 17(9): 561–565.
  37. Watanabe Y, Hozawa K, Hiroyoshi K, et al. The Importance of Patency of Tibial Run Off Arteries on Clinical Outcomes After Stenting for Chronic Total Occlusions in the Superficial Femoro-popliteal Artery. Eur J Vasc Endovasc Surg. 2018; 56(6): 857–863.
  38. Lazaris AM, Salas C, Tsiamis AC, et al. Factors affecting patency of subintimal infrainguinal angioplasty in patients with critical lower limb ischemia. Eur J Vasc Endovasc Surg. 2006; 32(6): 668–674.
  39. Pulli R, Dorigo W, Fargion A, et al. Comparison of early and midterm results of open and endovascular treatment of popliteal artery aneurysms. Ann Vasc Surg. 2012; 26(6): 809–818.
  40. Biancari F, Albäck A, Ihlberg L, et al. Angiographic runoff score as a predictor of outcome following femorocrural bypass surgery. Eur J Vasc Endovasc Surg. 1999; 17(6): 480–485.
  41. Rutherford RB, Baker JD, Ernst C, et al. Recommended standards for reports dealing with lower extremity ischemia: revised version. J Vasc Surg. 1997; 26(3): 517–538.
  42. Davies MG, Saad WE, Peden EK, et al. Percutaneous superficial femoral artery interventions for claudication--does runoff matter? Ann Vasc Surg. 2008; 22(6): 790–798.
  43. Kaisar J, Chen A, Cheung M, et al. Comparison of propaten heparin-bonded vascular graft with distal anastomotic patch versus autogenous saphenous vein graft in tibial artery bypass. Vascular. 2018; 26(2): 117–125.
  44. Spinosa DJ, Leung DA, Matsumoto AH, et al. Percutaneous intentional extraluminal recanalization in patients with chronic critical limb ischemia. Radiology. 2004; 232(2): 499–507.
  45. Rectenwald JE, Pretus HA, Seeger JM, et al. Potential predictors of outcome in patients with tissue loss who undergo infrainguinal vein bypass grafting. J Vasc Surg. 1999; 30(3): 427–435.
  46. Schwierz T, Pricop T, Ebner C, et al. The evaluation of run-off prior to infra-inguinal bypass reconstruction - a modified scoring system based on flow measurement. Eur J Vasc Endovasc Surg. 2003; 26(1): 52–58.
  47. Biancari F, Albäck A, Ihlberg L, et al. Angiographic runoff score as a predictor of outcome following femorocrural bypass surgery. Eur J Vasc Endovasc Surg. 1999; 17(6): 480–485.
  48. Peterkin GA, Manabe S, LaMorte WW, et al. Evaluation of a proposed standard reporting system for preoperative angiograms in infrainguinal bypass procedures: angiographic correlates of measured runoff resistance. J Vasc Surg. 1988; 7(3): 379–385.
  49. Kalman PG, Johnston KW, Walker PM, et al. Preoperative factors that predict hospital length of stay after distal arterial bypass. J Vasc Surg. 1994; 20(1): 70–75.
  50. Biancari F, Albäck A, Kantonen I, et al. Predictive factors for adverse outcome of pedal bypasses. Eur J Vasc Endovasc Surg. 1999; 18(2): 138–143.
  51. Normahani P, Anwar I, Courtney A, et al. Factors associated with infrainguinal bypass graft patency at 1-year; a retrospective analysis of a single centre experience. Perfusion. 2022; 37(3): 276–283.
  52. Cervin A, Tjärnström J, Ravn H, et al. Treatment of Popliteal Aneurysm by Open and Endovascular Surgery: A Contemporary Study of 592 Procedures in Sweden. Eur J Vasc Endovasc Surg. 2015; 50(3): 342–350.
  53. Frese JP, Schawe L, Carstens J, et al. A Modified Run-Off Resistance Score from Cross-Sectional Imaging Discriminates Chronic Critical Limb Ischemia from Intermittent Claudication in Peripheral Arterial Disease. Diagnostics. 2022; 12(12): 3155.
  54. Phair A, Hajibandeh S, Hajibandeh S, et al. Meta-analysis of posterior versus medial approach for popliteal artery aneurysm repair. J Vasc Surg. 2016; 64(4): 1141–1150.e1.
  55. Baccellieri D, Grandi A, Bilman V, et al. Early and mid-term outcomes of open popliteal artery aneurysm repair with prosthetic grafts. J Vasc Surg. 2022; 75(4): 1369–1376.
  56. Chang H, Veith FJ, Rockman CB, et al. Comparison of Outcomes for Open Popliteal Artery Aneurysm Repair Using Vein and Prosthetic Conduits. Ann Vasc Surg. 2021; 75: 69–78.
  57. Kopp R, Cascio R, Weidenhagen R, et al. Results of different operative procedures for patients with popliteal artery aneurysms. Vasa. 2006; 35(3): 185–190.
  58. Ravn H, Bergqvist D, Björck M, et al. Swedish Vascular Registry. Nationwide study of the outcome of popliteal artery aneurysms treated surgically. Br J Surg. 2007; 94(8): 970–977.
  59. Martelli E, Ippoliti A, Ventoruzzo G, et al. Popliteal artery aneurysms. Factors associated with thromboembolism and graft failure. Int Angiol. 2004; 23(1): 54–65.
  60. Troisi N, Masciello F, Michelagnoli S, et al. Outcomes of popliteal artery aneurysms treated by ligation and in-situ saphenous vein bypass. Int Angiol. 2021; 40(5): 435–441.