Vol 23, No 1 (2019)
REVIEW
Published online: 2018-10-08

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The role of aldosterone in kidney diseases and hypertension. Is it worth using mineralocorticoid receptor antagonists in clinical practice?

Rafał Łukasz Donderski1, Jacek Manitius1
Arterial Hypertension 2019;23(1):1-7.

Abstract

Aldosterone is a mineralocorticoid hormone which plays a pivotal role in water and electrolytes balance. Moreover,
aldosterone exerts a deleterious influence on the cardiovascular system and kidneys. In this review, we wanted to
show mechanisms of aldosterone related organ damage, the role of aldosterone in kidney diseases, hypertension and
therapeutic benefits related with aldosterone receptors blockade.

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