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Vol 21, No 4 (2017)
ORIGINAL PAPERS
Published online: 2017-08-11
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Valsalva manoeuvre increases vagal baroreceptor unload reflex sensitivity in young healthy subjects

Magdalena Wszedybyl-Winklewska, Andrzej F. Frydrychowski, Pawel J. Winklewski
DOI: 10.5603/AH.a2017.0016
·
Arterial Hypertension 2017;21(4):167-170.

open access

Vol 21, No 4 (2017)
ORIGINAL PAPERS
Published online: 2017-08-11

Abstract

Introduction. The objective was to verify the hypothesis that change in cardiovagal baroreceptor unload reflex sensitivity occurs between early phase 2 (VM2E) and phase 3 (VM3) of the Valsalva manoeuvre (VM). The study was performed on 29 volunteers between the ages of 25 and 40 (29.3 ± SE 4.0). Material and methods. The experimental scheme was as follows: rest in sitting position, VM in sitting position maintaining an expiratory pressure of 20 mm Hg for 15 seconds, rest in sitting position. Changes in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were measured using Finapres. Results. In VM2E and VM3, HR increased (+51.76 ± SE 4.06 beats/min., p < 0.001; +37.77 ± SE 8.65 beats/min., p < 0.0001, respectively) in response to a fall in SBP (–47.55 ± SE 3.95 mmHg, p < 0.001; –29.66 ± SE 2.80 mmHg, p < 0.0001; respectively). Both events of baroreceptor unload have been observed within the very similar range of SBP and HR. Conclusion. The slope of regression relating change in heart rate (DHR) and systolic arterial pressure (DSBP) was significantly higher in VM3 (DHR2 = –1.063 × DSBP2 + 7.0986) than in VM2E (DHR1 = –0.4395 × DSBP2 + 30.862), suggesting the increased baroreceptors’ sensitivity toward SBP fall in VM3 compared to VM2E. VM increases vagal baroreceptor unloads reflex sensitivity.

Abstract

Introduction. The objective was to verify the hypothesis that change in cardiovagal baroreceptor unload reflex sensitivity occurs between early phase 2 (VM2E) and phase 3 (VM3) of the Valsalva manoeuvre (VM). The study was performed on 29 volunteers between the ages of 25 and 40 (29.3 ± SE 4.0). Material and methods. The experimental scheme was as follows: rest in sitting position, VM in sitting position maintaining an expiratory pressure of 20 mm Hg for 15 seconds, rest in sitting position. Changes in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR) were measured using Finapres. Results. In VM2E and VM3, HR increased (+51.76 ± SE 4.06 beats/min., p < 0.001; +37.77 ± SE 8.65 beats/min., p < 0.0001, respectively) in response to a fall in SBP (–47.55 ± SE 3.95 mmHg, p < 0.001; –29.66 ± SE 2.80 mmHg, p < 0.0001; respectively). Both events of baroreceptor unload have been observed within the very similar range of SBP and HR. Conclusion. The slope of regression relating change in heart rate (DHR) and systolic arterial pressure (DSBP) was significantly higher in VM3 (DHR2 = –1.063 × DSBP2 + 7.0986) than in VM2E (DHR1 = –0.4395 × DSBP2 + 30.862), suggesting the increased baroreceptors’ sensitivity toward SBP fall in VM3 compared to VM2E. VM increases vagal baroreceptor unloads reflex sensitivity.
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Keywords

Valsalva manoeuvre, baroreceptor reflex, vagal baroreflex sensitivity, vagal baroreflex unload

About this article
Title

Valsalva manoeuvre increases vagal baroreceptor unload reflex sensitivity in young healthy subjects

Journal

Arterial Hypertension

Issue

Vol 21, No 4 (2017)

Pages

167-170

Published online

2017-08-11

DOI

10.5603/AH.a2017.0016

Bibliographic record

Arterial Hypertension 2017;21(4):167-170.

Keywords

Valsalva manoeuvre
baroreceptor reflex
vagal baroreflex sensitivity
vagal baroreflex unload

Authors

Magdalena Wszedybyl-Winklewska
Andrzej F. Frydrychowski
Pawel J. Winklewski

References (8)
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