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Vol 29, No 4 (2023)
Research paper
Published online: 2023-12-21

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Comparing two risk scores for predictive ability of contrast-induced nephropathy development in patients presenting with chronic coronary syndrome

Sevgi Özcan1, Esra Dönmez1, İrfan Şahin1, Ertuğrul Okuyan1
Acta Angiologica 2023;29(4):133-140.

Abstract

Introduction: This study aimed to investigate the roles of ATRIA and CHA2DS2-VASc scores in predicting contrast-induced nephropathy (CIN) development risk in patients presenting with chronic coronary syndromes (CCS) and undergoing elective percutaneous coronary intervention (PCI).

Material and methods: Patients who underwent coronary angiography due to diagnosis of CCS and decided to be treated with PCI between 2018 and 2020 were included in this retrospective single-centre study.

Results: A total of 447 patients were included. DM [p < 0.0001, β: 0.263, OR (95%CI): 0.187–0.459], CHF [p = 0.035, β: 0.384, OR (95%CI): 0.158–0.934], the volume of CA [p = 0.020, β: 0.145, OR (95%CI): 0.112–0.393], ATRIA [p = 0.001, β: 3.453, OR (95%CI): 1.132–6.148] and CHA2DS2-VASc [p < 0.0001, β: 3.120, OR (95%CI): 1.925–5.056] scores were found as independent risk factors associated with CIN development. The AUC for the ATRIA score was 0.779 [%95CI: 0.717–0.842]. A cutoff value of 4.5 for the ATRIA score was associated with 74.1% sensitivity and 67.3% specificity in the prediction of CIN development. Moreover, the AUC for the CHA2DS2-VASc score was 0.869 [%95CI: 0.825–0.912]. A cutoff value of 3.5 for the CHA2DS2-VASc score was associated with 81.5% sensitivity and 76.1% specificity in the prediction of CIN development.

Conclusion: ATRIA and CHA2DS2-VASc scores may be used as a marker of CIN development in CCS patients
who underwent elective PCI and both scores may be used to define patients under risk in a practical way.

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