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open access

Vol 5, No 1 (2003)
Prace poglądowe
Published online: 2003-05-15
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Progressing stroke

Magdalena Nowaczewska, Barbara Książkiewicz
Udar Mózgu. Problemy Interdyscyplinarne 2003;5(1):17-22.

open access

Vol 5, No 1 (2003)
Prace poglądowe
Published online: 2003-05-15

Abstract

Progressing stroke is a poorly understood, multifactoral event only partially predictable by means of clinical, laboratory and imaging data currently available in clinical practice. The hemodynamic changes in local cerebral blood flow and the biochemical mechanisms that influence on evolution of ischemic penumbra are crucial in the early neurologic deterioration of acute stroke, although systemic factors may have additional worsening effects. Trombolytic and neuroprotective drugs are the more promising group to salvage potentially reversible ischemic tissue and improve functional outcome. However, for the best treatment choices we need to advance knowledge of new diagnostic processes especially neuroimaging techniques and biochemical markers. Only then the selection of patients and giving them appropriate treatment would be possible.

Abstract

Progressing stroke is a poorly understood, multifactoral event only partially predictable by means of clinical, laboratory and imaging data currently available in clinical practice. The hemodynamic changes in local cerebral blood flow and the biochemical mechanisms that influence on evolution of ischemic penumbra are crucial in the early neurologic deterioration of acute stroke, although systemic factors may have additional worsening effects. Trombolytic and neuroprotective drugs are the more promising group to salvage potentially reversible ischemic tissue and improve functional outcome. However, for the best treatment choices we need to advance knowledge of new diagnostic processes especially neuroimaging techniques and biochemical markers. Only then the selection of patients and giving them appropriate treatment would be possible.
Get Citation

Keywords

progressing stroke; definitions; diagnostic criteria; risk factors; mechanisms; treatment

About this article
Title

Progressing stroke

Journal

Interdisciplinary Problems of Stroke

Issue

Vol 5, No 1 (2003)

Pages

17-22

Published online

2003-05-15

Bibliographic record

Udar Mózgu. Problemy Interdyscyplinarne 2003;5(1):17-22.

Keywords

progressing stroke
definitions
diagnostic criteria
risk factors
mechanisms
treatment

Authors

Magdalena Nowaczewska
Barbara Książkiewicz

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