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Vol 5, No 1 (2003)
Prace oryginalne
Published online: 2003-05-15
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Dynamic changes of the CT examination in ischemic stroke and connection with risk factors and prognostic significance

Dagmara Sobczyńska, Zdzisław Maciejek, Przemysław Czyszkowski
Udar Mózgu. Problemy Interdyscyplinarne 2003;5(1):1-5.

open access

Vol 5, No 1 (2003)
Prace oryginalne
Published online: 2003-05-15

Abstract

Background. The aim of study is to estimate the changes in CT picture in ischemic stroke and their connection with the extent of brain lesions as well as with the risks factors and prognostic significance.
Material and methods. A consecutive series of 371 patients aged from 32 to 88 (Mean age 65.6) with ischemic stroke (170 women, 201 men). The diagnosis was made on the basis of clinical picture and repeated CT of the head on the 1–7 day of stroke and 4–5 week of stroke in patient with severe motoric deficit on admission. All the patients during the treatment were given aspirin, low-molecular-weight heparin 3800 U aXa or 7600 U aXa.
Results. The presence of hypodense area was found in 299 patients (79%); among these: on the 1st day of stroke hypodense area was found in 61 cases (20.4%), in days 2 to 7 in 238 patients (79.6%). Hemorrhagic transformation was observed in days 2 to 7 of stroke in 12 patients (3.2%), which was significantly correlated with the initial elevation of blood pressure (> 180/100 mm Hg), diabetes mellitus, cardiac arrhythmia, hyperthermia and with the presence of extensive hypodense area in the area supplied by middle cerebral artery with the effect of mass. Coexistence more than two risks factors (hypertension, cardiac arrhythmia, diabetes mellitus) correlated with the extent of infarct focus, hemorrhagic transformation, severity of neurological deficit (ADL 0–6), the poor improvement of motoric function (ADL 2–10) and poor prognosis (28-day mortality - 33 patients - 11%). The absence of hypodense areas on the first day CT in ischemic stroke did not influence the prognosis.
Conclusions. The extent of infarct focus, hemorrhagic transformation, coexisting hypertension, cardiac arrhythmia and diabetes mellitus to was correlated significantly with poorer prognosis and early 28-day mortality.

Abstract

Background. The aim of study is to estimate the changes in CT picture in ischemic stroke and their connection with the extent of brain lesions as well as with the risks factors and prognostic significance.
Material and methods. A consecutive series of 371 patients aged from 32 to 88 (Mean age 65.6) with ischemic stroke (170 women, 201 men). The diagnosis was made on the basis of clinical picture and repeated CT of the head on the 1–7 day of stroke and 4–5 week of stroke in patient with severe motoric deficit on admission. All the patients during the treatment were given aspirin, low-molecular-weight heparin 3800 U aXa or 7600 U aXa.
Results. The presence of hypodense area was found in 299 patients (79%); among these: on the 1st day of stroke hypodense area was found in 61 cases (20.4%), in days 2 to 7 in 238 patients (79.6%). Hemorrhagic transformation was observed in days 2 to 7 of stroke in 12 patients (3.2%), which was significantly correlated with the initial elevation of blood pressure (> 180/100 mm Hg), diabetes mellitus, cardiac arrhythmia, hyperthermia and with the presence of extensive hypodense area in the area supplied by middle cerebral artery with the effect of mass. Coexistence more than two risks factors (hypertension, cardiac arrhythmia, diabetes mellitus) correlated with the extent of infarct focus, hemorrhagic transformation, severity of neurological deficit (ADL 0–6), the poor improvement of motoric function (ADL 2–10) and poor prognosis (28-day mortality - 33 patients - 11%). The absence of hypodense areas on the first day CT in ischemic stroke did not influence the prognosis.
Conclusions. The extent of infarct focus, hemorrhagic transformation, coexisting hypertension, cardiac arrhythmia and diabetes mellitus to was correlated significantly with poorer prognosis and early 28-day mortality.
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Keywords

ischemic stroke; computer tomography; risk factors; prognosis

About this article
Title

Dynamic changes of the CT examination in ischemic stroke and connection with risk factors and prognostic significance

Journal

Interdisciplinary Problems of Stroke

Issue

Vol 5, No 1 (2003)

Pages

1-5

Published online

2003-05-15

Bibliographic record

Udar Mózgu. Problemy Interdyscyplinarne 2003;5(1):1-5.

Keywords

ischemic stroke
computer tomography
risk factors
prognosis

Authors

Dagmara Sobczyńska
Zdzisław Maciejek
Przemysław Czyszkowski

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