Shortcuts

open access

Vol 11, No 2 (2009)
Prace poglądowe
Published online: 2010-03-11
Get Citation

Experimental animals models of cerebral ischaemia

Przemysław Kowiański, Grażyna Lietzau, Jerzy Dziewiątkowski, Janusz Moryś
Udar Mózgu. Problemy Interdyscyplinarne 2009;11(2):70-79.

open access

Vol 11, No 2 (2009)
Prace poglądowe
Published online: 2010-03-11

Abstract

Unsatisfactory cerebral ischaemic stroke treatment make understanding of pathophysiology of this process and developing effective therapies the focus of interest of many scientific disciplines. Both these goals can be achieved in the course of basic and clinical research. A large body of information concerning this issue is controversial. Animal ischaemic models seem to be a very useful tool for biochemical and pathophysiological research; however their employment in new drug development research is widely questioned. In this report we discuss the most widely used experimental models of the ischaemic stroke, their advantages and disadvantages, and possible reasons for discrepancy in results of basic and clinical research.
Interdisciplinary Problems of Stroke; 11 (2): 70-79

Abstract

Unsatisfactory cerebral ischaemic stroke treatment make understanding of pathophysiology of this process and developing effective therapies the focus of interest of many scientific disciplines. Both these goals can be achieved in the course of basic and clinical research. A large body of information concerning this issue is controversial. Animal ischaemic models seem to be a very useful tool for biochemical and pathophysiological research; however their employment in new drug development research is widely questioned. In this report we discuss the most widely used experimental models of the ischaemic stroke, their advantages and disadvantages, and possible reasons for discrepancy in results of basic and clinical research.
Interdisciplinary Problems of Stroke; 11 (2): 70-79
Get Citation

Keywords

experimental model; neuroprotection; ischaemia; rat; stroke

About this article
Title

Experimental animals models of cerebral ischaemia

Journal

Interdisciplinary Problems of Stroke

Issue

Vol 11, No 2 (2009)

Pages

70-79

Published online

2010-03-11

Bibliographic record

Udar Mózgu. Problemy Interdyscyplinarne 2009;11(2):70-79.

Keywords

experimental model
neuroprotection
ischaemia
rat
stroke

Authors

Przemysław Kowiański
Grażyna Lietzau
Jerzy Dziewiątkowski
Janusz Moryś

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl