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open access

Vol 12, No 1-2 (2010)
Prace poglądowe
Published online: 2011-07-05
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Venous stroke in the course of malignancy

Sławomir Michalak, Wojciech Kozubski
Udar Mózgu. Problemy Interdyscyplinarne 2010;12(1-2):42-46.

open access

Vol 12, No 1-2 (2010)
Prace poglądowe
Published online: 2011-07-05

Abstract

Developing malignancy is associated with venous thromboembolism and venous stroke. Age, obesity, history of breast, lung, colorectal and ovarian cancer as well as thromboembolic event increase the risk. Pathomechanisms of such complications include procoagulants secreted by malignant cells, proinflammatory cytokines produced in response to growing tumor, activation of platelets and monocytes. The diagnostics is based on clinical manifestation, neuroimaging and routine laboratory tests: platelets and white blood cells counts, D-dimers and C-reactive protein concentrations. Highly advanced laboratory tests, that enable prognosis of risk can be used as well: prothrombin fragment 1+2, clotting factor VIII, soluble P-selectin and tissue factor.
Interdisciplinary Problems of Stroke 2010; 12 (1–2): 42–46

Abstract

Developing malignancy is associated with venous thromboembolism and venous stroke. Age, obesity, history of breast, lung, colorectal and ovarian cancer as well as thromboembolic event increase the risk. Pathomechanisms of such complications include procoagulants secreted by malignant cells, proinflammatory cytokines produced in response to growing tumor, activation of platelets and monocytes. The diagnostics is based on clinical manifestation, neuroimaging and routine laboratory tests: platelets and white blood cells counts, D-dimers and C-reactive protein concentrations. Highly advanced laboratory tests, that enable prognosis of risk can be used as well: prothrombin fragment 1+2, clotting factor VIII, soluble P-selectin and tissue factor.
Interdisciplinary Problems of Stroke 2010; 12 (1–2): 42–46
Get Citation

Keywords

venous stroke; malignancy; hemostatic disorders

About this article
Title

Venous stroke in the course of malignancy

Journal

Interdisciplinary Problems of Stroke

Issue

Vol 12, No 1-2 (2010)

Pages

42-46

Published online

2011-07-05

Bibliographic record

Udar Mózgu. Problemy Interdyscyplinarne 2010;12(1-2):42-46.

Keywords

venous stroke
malignancy
hemostatic disorders

Authors

Sławomir Michalak
Wojciech Kozubski

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