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open access

Vol 1, No 2 (2003)
Prace poglądowe (nadesłane)
Published online: 2003-10-22
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Phosphodiesterase-5 inhibitors - similarities and differences

Zbigniew Lew-Starowicz
Seksuologia Polska 2003;1(2):79-82.

open access

Vol 1, No 2 (2003)
Prace poglądowe (nadesłane)
Published online: 2003-10-22

Abstract

Inhibitors of phosphodiesterase-5 are the agebts of thefirst projection in ED treatment. Nowadays the three drugs of this group are being appplied: Sildenafil (Viagra), Vardenafil (Levitra) oraz Tadalafil (Cialis). The author compares these three drugs, basing on the literature. The most studied and the richest literature has Sildenafil. The chemical stucture and period of activity differs these three agents. The drugs action mechanism is the same for every drug. Vardenafils accuracy is 85% in 20 mg dose (moderate ED) and 39% with deep ED. it is also the agest, which can be used when there is no response for Slidenafil. Tadalafil’s accuracy was 87% in 20 mg and Sildenafil 83%. The studies showed different patient preferences in choosing the drug: 17.4% preffers Sildenafil, 43% Vardenafil, 39% Tadalafil. All agents are effective in diabetes.

Abstract

Inhibitors of phosphodiesterase-5 are the agebts of thefirst projection in ED treatment. Nowadays the three drugs of this group are being appplied: Sildenafil (Viagra), Vardenafil (Levitra) oraz Tadalafil (Cialis). The author compares these three drugs, basing on the literature. The most studied and the richest literature has Sildenafil. The chemical stucture and period of activity differs these three agents. The drugs action mechanism is the same for every drug. Vardenafils accuracy is 85% in 20 mg dose (moderate ED) and 39% with deep ED. it is also the agest, which can be used when there is no response for Slidenafil. Tadalafil’s accuracy was 87% in 20 mg and Sildenafil 83%. The studies showed different patient preferences in choosing the drug: 17.4% preffers Sildenafil, 43% Vardenafil, 39% Tadalafil. All agents are effective in diabetes.
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Keywords

PDE-5 inhibitors; mechanisms of action

About this article
Title

Phosphodiesterase-5 inhibitors - similarities and differences

Journal

Seksuologia Polska (Polish Sexology)

Issue

Vol 1, No 2 (2003)

Pages

79-82

Published online

2003-10-22

Bibliographic record

Seksuologia Polska 2003;1(2):79-82.

Keywords

PDE-5 inhibitors
mechanisms of action

Authors

Zbigniew Lew-Starowicz

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