open access
Vol 1, No 2 (2003)
Prace poglądowe (nadesłane)
Published online: 2003-10-22
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Phosphodiesterase-5 inhibitors - similarities and differences
Zbigniew Lew-Starowicz
Seksuologia Polska 2003;1(2):79-82.
open access
Vol 1, No 2 (2003)
Prace poglądowe (nadesłane)
Published online: 2003-10-22
Abstract
Inhibitors of phosphodiesterase-5 are the agebts of thefirst projection in ED treatment. Nowadays the three
drugs of this group are being appplied: Sildenafil (Viagra), Vardenafil (Levitra) oraz Tadalafil (Cialis). The
author compares these three drugs, basing on the literature. The most studied and the richest literature
has Sildenafil. The chemical stucture and period of activity differs these three agents. The drugs action
mechanism is the same for every drug. Vardenafils accuracy is 85% in 20 mg dose (moderate ED) and 39%
with deep ED. it is also the agest, which can be used when there is no response for Slidenafil. Tadalafil’s
accuracy was 87% in 20 mg and Sildenafil 83%. The studies showed different patient preferences in choosing
the drug: 17.4% preffers Sildenafil, 43% Vardenafil, 39% Tadalafil. All agents are effective in
diabetes.
Abstract
Inhibitors of phosphodiesterase-5 are the agebts of thefirst projection in ED treatment. Nowadays the three
drugs of this group are being appplied: Sildenafil (Viagra), Vardenafil (Levitra) oraz Tadalafil (Cialis). The
author compares these three drugs, basing on the literature. The most studied and the richest literature
has Sildenafil. The chemical stucture and period of activity differs these three agents. The drugs action
mechanism is the same for every drug. Vardenafils accuracy is 85% in 20 mg dose (moderate ED) and 39%
with deep ED. it is also the agest, which can be used when there is no response for Slidenafil. Tadalafil’s
accuracy was 87% in 20 mg and Sildenafil 83%. The studies showed different patient preferences in choosing
the drug: 17.4% preffers Sildenafil, 43% Vardenafil, 39% Tadalafil. All agents are effective in
diabetes.
Get Citation
Keywords
PDE-5 inhibitors; mechanisms of action
About this articleTitle
Phosphodiesterase-5 inhibitors - similarities and differences
Journal
Seksuologia Polska (Polish Sexology)
Issue
Pages
79-82
Published online
2003-10-22
Bibliographic record
Seksuologia Polska 2003;1(2):79-82.
Keywords
PDE-5 inhibitors
mechanisms of action
Authors
Zbigniew Lew-Starowicz