Vol 27, No 2 (2022)
Research paper
Published online: 2022-03-14
Radiotherapy during the COVID-19: a review about management and treatment strategies
Rep Pract Oncol Radiother 2022;27(2):291-302.
Abstract
Background: The administration of radiotherapy should be encouraged despite the emergency of COVID-19; therefore, our aim is to analyze management and therapeutic interventions to be implemented in a Radiotherapy department to allow patients to continue their treatment and health professionals to continue their work safely.
Material and methods: A Pubmed search was performed, in which all articles specific to Radiotherapy and COVID-19 were included. Those articles that were too specific about the COVID-19, surgery and chemiotherapy, were excluded.
Results: 315 articles were selected, of which 35 were about therapeutic strategies and 25 about management strategies. In the first category, 5 articles were about how radiotherapy could be a weapon to be used for COVID-19 positive patients with important lung problems. While 30 articles described priorities and new treatment plans for oncology patients who have to undergo radiotherapy during the pandemic. In the second category, almost all the articles explained how triage can be a preventive and monitoring way against COVID-19 in an operating unit with many patients and professionals, and other articles developed a telemedicine system, too, which allows patients to make scheduled visits without coming to the hospital and also for the staff, who can work remotely. In addition, 5 articles concerning psychological aspects of both patients and health care providers were included.
Conclusion: This document can be used as a summary in the coming months/years, during the recovery phase from COVID19 pandemic outbreak and as a starting point to be used in case of further pandemic break-out.
Keywords: radiotherapyCOVID19management
References
- Giotta F, Romito F, Lagatolla F, et al. Psychological Resilience in Cancer Patients and Survivors During The Covid-19 Pandemic. J Cancer Rehabil. 2020; 3: 29.
- Zorina T, Styche A. Infectious Diseases in Cancer Patients: An Overview. Infect. Cancer Bi-Directorial Interact. Springer International Publishing, Cham 2015: 295–311.
- Gupta M, Ahuja R, Gupta S, et al. Running of high patient volume radiation oncology department during COVID-19 crisis in India: our institutional strategy. Radiat Oncol J. 2020; 38(2): 93–98.
- Amaoui B, Semghouli S, Benjaafar N. Organization of a radiotherapy service during the COVID-19 epidemic: Experience of Regional Center of Oncology of Agadir, Morocco. Radiography (Lond). 2020; 26(4): e312–e314.
- Wei W, Zheng D, Lei Yu, et al. Radiotherapy workflow and protection procedures during the Coronavirus Disease 2019 (COVID-19) outbreak: Experience of the Hubei Cancer Hospital in Wuhan, China. Radiother Oncol. 2020; 148: 203–210.
- Zhang D, Li T, Wang P, et al. Experts consensus on epidemic prevention and control in radiotherapy centers during the COVID-19 outbreak: Experiences from Sichuan Province. Clin Transl Radiat Oncol. 2020; 24: 88–91.
- Tsang Y, Duffton A, Leech M, et al. ESTRO RTTC. Meeting the challenges imposed by COVID-19: Guidance document by the ESTRO Radiation TherapisT Committee (RTTC). Tech Innov Patient Support Radiat Oncol. 2020; 15: 6–10.
- Montesi G, Di Biase S, Chierchini S, et al. Radiotherapy during COVID-19 pandemic. How to create a No fly zone: a Northern Italy experience. Radiol Med. 2020; 125(6): 600–603.
- Combs SE, Belka C, Niyazi M, et al. First statement on preparation for the COVID-19 pandemic in large German Speaking University-based radiation oncology departments. Radiat Oncol. 2020; 15(1): 74.
- Anderson N, Thompson K, Andrews J, et al. Planning for a pandemic: Mitigating risk to radiation therapy service delivery in the COVID-19 era. J Med Radiat Sci. 2020; 67(3): 243–248.
- Tey J, Ho S, Choo BAi, et al. Navigating the challenges of the COVID-19 outbreak: Perspectives from the radiation oncology service in Singapore. Radiother Oncol. 2020; 148: 189–193.
- Gregucci F, Caliandro M, Surgo A, et al. Cancer patients in Covid-19 era: Swimming against the tide. Radiother Oncol. 2020; 149: 109–110.
- Mazza M, Marano G, Traversi G, et al. Emotional Health and Mental Coaching: Safeguarding Oncological Patients’ Mental Health in the COVID-19 Era. Clin Oncol Res. 2021: 1–3.
- Salute ISS. Rapporto ISS: Indicazioni ad interim per un appropriato sostegno degli operatori sanitari e sociosanitari durante lo scenario emergenziale SARS-COV-2 2020.
- Marconi E, Chiesa S, Dinapoli L, et al. A radiotherapy staff experience of gratitude during COVID-19 pandemic. Tech Innov Patient Support Radiat Oncol. 2021; 18: 32–34.
- Teckie S, Koffler D, Potters L. The Resilience of Radiation Oncology in the COVID Era and Beyond. Int J Radiat Oncol Biol Phys. 2020; 108(2): 364–369.
- Simcock R, Vengaloor T, Estes C, et al. COVID-19: Global radiation oncology’s targeted response for pandemic preparedness. Clin Transl Radiat Oncol. 2020; 22: 55–68.
- Viale G, Licata L, Sica L, et al. Personalized Risk-Benefit Ratio Adaptation of Breast Cancer Care at the Epicenter of COVID-19 Outbreak. Oncologist. 2020; 25(7): e1013–e1020.
- de Azambuja E, Trapani D, Loibl S, et al. ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer. ESMO Open. 2020; 5(Suppl 3).
- Kabeer KK, Jafferbhoy S, Marla S, et al. Breast Cancer Management Guidelines During COVID-19 Pandemic. Indian J Surg. 2020 [Epub ahead of print]: 1–8.
- Mendez LC, Raziee H, Davidson M, et al. Should we embrace hypofractionated radiotherapy for cervical cancer? A technical note on management during the COVID-19 pandemic. Radiother Oncol. 2020; 148: 270–273.
- Elledge CR, Beriwal S, Chargari C, et al. Radiation therapy for gynecologic malignancies during the COVID-19 pandemic: International expert consensus recommendations. Gynecol Oncol. 2020; 158(2): 244–253.
- Srinivasa GY, Dey T, Suri V, et al. Rationalizing Treatment for Gynecological Cancers During the COVID-19 Pandemic: An Indian Experience. Indian J Gynecol Oncol. 2020; 18(3): 101.
- Kang JJ, Wong RJ, Sherman EJ, et al. The 3 Bs of cancer care amid the COVID-19 pandemic crisis: "Be safe, be smart, be kind"-A multidisciplinary approach increasing the use of radiation and embracing telemedicine for head and neck cancer. Cancer. 2020; 126(18): 4092–4104.
- De Felice F, D'Angelo E, Ingargiola R, et al. A snapshot on radiotherapy for head and neck cancer patients during the COVID-19 pandemic: a survey of the Italian Association of Radiotherapy and Clinical Oncology (AIRO) head and neck working group. Radiol Med. 2021; 126(2): 343–347.
- Vreugdenhil M, Fong C, Sanghera P, et al. Hypofractionated chemoradiation for head and cancer: Data from the PET NECK trial. Oral Oncol. 2021; 113: 105112.
- Gupta T, Ghosh-Laskar S, Agarwal JP. Resource-sparing curative-intent hypofractionated-accelerated radiotherapy in head and neck cancer: More relevant than ever before in the COVID era. Oral Oncol. 2020; 111: 105045.
- Alterio D, Volpe S, Marvaso G, et al. Head and neck cancer radiotherapy amid COVID-19 pandemic: Report from Milan, Italy. Head Neck. 2020; 42(7): 1482–1490.
- Yanagihara TK, Holland RE, Chera B. Practical Challenges of Mask-to-Mask Encounters with Patients with Head and Neck Cancers amid the Coronavirus Disease 2019 Pandemic. Adv Radiat Oncol. 2020; 5(4): 651–655.
- Couñago F, Navarro-Martin A, Luna J, et al. GOECP/SEOR clinical recommendations for lung cancer radiotherapy during the COVID-19 pandemic. World J Clin Oncol. 2020; 11(8): 510–527.
- Faivre-Finn C, Fenwick JD, Franks KN, et al. Reduced Fractionation in Lung Cancer Patients Treated with Curative-intent Radiotherapy during the COVID-19 Pandemic. Clin Oncol (R Coll Radiol). 2020; 32(8): 481–489.
- Passaro A, Addeo A, Von Garnier C, et al. ESMO Management and treatment adapted recommendations in the COVID-19 era: Lung cancer. ESMO Open. 2020; 5(Suppl 3).
- Zaorsky NG, Yu JB, McBride SM, et al. Prostate Cancer Radiation Therapy Recommendations in Response to COVID-19. Adv Radiat Oncol. 2020; 5(4): 659–665.
- Obek C, Doganca T, Argun OB, et al. Management of prostate cancer patients during COVID-19 pandemic. Prostate Cancer Prostatic Dis. 2020; 23(3): 398–406.
- Thureau S, Faivre JC, Assaker R, et al. Adapting palliative radiation therapy for bone metastases during the Covid-19 pandemic: GEMO position paper. J Bone Oncol. 2020; 22: 100291.
- Yerramilli D, Xu AJ, Gillespie EF, et al. Palliative Radiation Therapy for Oncologic Emergencies in the Setting of COVID-19: Approaches to Balancing Risks and Benefits. Adv Radiat Oncol. 2020; 5(4): 589–594.
- Janssens GO, Mandeville HC, Timmermann B, et al. A rapid review of evidence and recommendations from the SIOPE radiation oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises. Radiother Oncol. 2020; 148: 216–222.
- ElMajjaoui S, Ismaili N, Benjaafar N. COVID-19, Brachytherapy, and Gynecologic Cancers: a Moroccan Experience. SN Compr Clin Med. 2020 [Epub ahead of print]: 1–4.
- Elledge CR, Beriwal S, Chargari C, et al. Radiation therapy for gynecologic malignancies during the COVID-19 pandemic: International expert consensus recommendations. Gynecol Oncol. 2020; 158(2): 244–253.
- Williams VM, Kahn JM, Harkenrider MM, et al. COVID-19 impact on timing of brachytherapy treatment and strategies for risk mitigation. Brachytherapy. 2020; 19(4): 401–411.
- Aghili M, Jafari F, Vand Rajabpoor M. Brachytherapy during the coronavirus disease 2019 - Lessons from Iran. Brachytherapy. 2020; 19(4): 412–414.
- Arruda GV, Weber RR, Bruno AC, et al. The risk of induced cancer and ischemic heart disease following low dose lung irradiation for COVID-19: estimation based on a virtual case. Int J Radiat Biol. 2021; 97(2): 120–125.
- Del Castillo R, Martinez D, Sarria GJ, et al. Low-dose radiotherapy for COVID-19 pneumonia treatment: case report, procedure, and literature review. Strahlenther Onkol. 2020; 196(12): 1086–1093.
- Hanekamp YN, Giordano J, Hanekamp JC, et al. Immunomodulation Through Low-Dose Radiation for Severe COVID-19: Lessons From the Past and New Developments. Dose Response. 2020; 18(3): 1559325820956800.
- WHO global influenza preparedness plan The role of WHO and recommendations for national measures before and during pandemics. https://www.who.int/csr/resources/publications/influenza/en/WHO_CDS_CSR_GIP_2005_5.pdf.