Vol 27, No 2 (2022)
Research paper
Published online: 2022-02-08

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The utility of 18F-FDG PET/CT in brain tumours diagnosis

Agata Pietrzak12, Andrzej Marszałek3, Tomasz Piotrowski14, Katarzyna Pietrasz2, Adrianna Medak5, Julia Wojtowicz6, Hubert Szweda4, Krzysztof Matuszewski4, Witold Cholewiński21
Rep Pract Oncol Radiother 2022;27(2):235-240.


Background: The purpose of the study was to discuss whether 2-deoxy-2-[18F]fluoro-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) study protocol should include brain imaging.

Materials and methods: Analysis of international societies recommendations compared with the original data obtained in over 1000 consecutive torso and brain 18F-FDG PET/CT studies collected in 2010.

Results: According to the international societies recommendations, the 18F-FDG should not be the radiotracer of choice considering the brain region PET/CT study. However, it can be performed as an additional brain imaging tool. Based on at least a 3-year follow-up, we detected 8 cases of suspicious brain findings and no primary lesion among over 1000 consecutive torso and brain 18F-FDG PET/CT scans performed in 2010. However, in 5 out of 8 patients, the brain lesion was the only metastasis detected, affecting further therapy.

Conclusions: The 18F-FDG PET/CT study may help detect malignant brain lesions and, therefore, including brain region imaging into the study protocol should be considered. 

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