Vol 26, No 6 (2021)
Research paper
Published online: 2021-11-05

open access

Page views 6237
Article views/downloads 498
Get Citation

Connect on Social Media

Connect on Social Media

The effects of foot reflexology on pain and physiological indicators in children with leukemia under chemotherapy: a clinical trial study

Fereshteh Ghaljaei1, Alia Jalalodini1
Rep Pract Oncol Radiother 2021;26(6):955-961.

Abstract

Background: Foot reflexology is a popular complementary medicine method; however, previous studies have shown conflicting results. This study aimed to investigate the impact of foot reflexology on pain and physiological responses caused by intrathecal injection of chemotherapy drugs in children with leukemia.

Materials and methods: This clinical trial included 80 children with leukemia. The participants received 20 min foot reflexology (10 min each foot). The primary measured outcomes included pain and physiological indicators (blood pressure and heart rate).

Results: The results showed that foot reflexology had a significant effect on reducing pain (p = 0.002) and improving physiological indicators [blood pressure (p = 0.002) and heart rate (p = 0.003)].

Conclusion: Based on the results of the present study, which shows the positive effect of foot reflexology on the improvement of pain and physiological indicators, foot reflexology can be used as a complementary treatment along with conventional therapies.

Article available in PDF format

View PDF Download PDF file

References

  1. Kantarjian HM, Kadia TM, DiNardo CD, et al. Acute myeloid leukemia: Treatment and research outlook for 2021 and the MD Anderson approach. Cancer. 2021; 127(8): 1186–1207.
  2. Dong Y, Shi O, Zeng Q, et al. Leukemia incidence trends at the global, regional, and national level between 1990 and 2017. Exp Hematol Oncol. 2020; 9: 14.
  3. Globocan (2021) Cancers in Iran https://gco.iarc.fr/today/online-analysis-table? v=2020&mode=cancer&mode_population=continents&population=900&populations=364&key=asr&sex=0&cancer=39&type=0&statistic=5&prevalence=0&population_group=0&ages_group%5B%5D=0&ages_group%5B%5D=17&group_cancer=1&include_nmsc=1&include_nmsc_other=1..
  4. Bramati P, Hui D, Bruera E. Integrated Palliative and Oncology Care for Patients With Acute Myeloid Leukemia-Moving From Evidence to Practice. JAMA Oncol. 2021; 7(6): 943.
  5. Estey E. New treatments for acute myeloid leukemia: how much has changed? Leukemia. 2021; 35(1): 45–46.
  6. Locatelli F, Zugmaier G, Rizzari C, et al. Effect of Blinatumomab vs Chemotherapy on Event-Free Survival Among Children With High-risk First-Relapse B-Cell Acute Lymphoblastic Leukemia: A Randomized Clinical Trial. JAMA. 2021; 325(9): 843–854.
  7. de Kruif AJ, Westerman MJ, Winkels RM, et al. Exploring changes in dietary intake, physical activity and body weight during chemotherapy in women with breast cancer: A Mixed-Methods Study. J Hum Nutr Diet. 2021; 34(3): 550–561.
  8. Ai YT, Hu H, Yang CM, et al. Hindrances of peripherally inserted central catheter care of leukemia patients: a qualitative study. Support Care Cancer. 2021; 29(8): 4339–4347.
  9. Forsythe A, Sandman K. What Does the Economic Burden of Acute Myeloid Leukemia Treatment Look Like for the Next Decade? An Analysis of Key Findings, Challenges and Recommendations. J Blood Med. 2021; 12: 245–255.
  10. Damayanti R, Allenidekania A. The correlation between the quality of pain and fatigue in children with acute lymphoblastic leukemia (ALL). Enfermer Clín. 2021; 31: S330–S333.
  11. Barzilai-Birenboim S, Yacobovich J, Zalcberg Y, et al. Bone pain at leukemia diagnosis and other risk factors for symptomatic osteonecrosis in children with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2021; 68(8): e29033.
  12. Miladinia M, Voss JG, Molavynejad S, et al. Slow-Stroke Back Massage Compared With Music Therapy for Leukemia-Related Pain and Fatigue: A Randomized Controlled Trial. JCO Oncol Pract. 2021 [Epub ahead of print]: OP2100156.
  13. Ng JY, Sharma AE. Guidelines for Cancer-Related Pain: A Systematic Review of Complementary and Alternative Medicine Recommendations. Pain Pract. 2021; 21(4): 454–467.
  14. Zhang C, Xiao J, Yu Z, et al. Cancer pain management and the roles of pharmacists in China. Int J Clin Pharm. 2021; 43(2): 383–385.
  15. Ciarlo G, Ahmadi E, Welter S, et al. Factors influencing the usage of complementary and alternative medicine by patients with cancer. Complement Ther Clin Pract. 2021; 44: 101389.
  16. Huang HC, Chen KH, Kuo SF, et al. Can foot reflexology be a complementary therapy for sleep disturbances? Evidence appraisal through a meta-analysis of randomized controlled trials. J Adv Nurs. 2021; 77(4): 1683–1697.
  17. Taheri H, Naseri-Salahshour V, Abedi A, et al. Comparing the Effect of Foot and Hand Reflexology on Pain Severity after Appendectomy: A Randomized Clinical Trial. Iran J Nurs Midwifery Res. 2019; 24(6): 451–456.
  18. Singh P, Chaturvedi A. Complementary and alternative medicine in cancer pain management: a systematic review. Indian J Palliat Care. 2015; 21(1): 105–115.
  19. Ghazavi A, Pouraboli B, Sabzevari S, et al. Evaluation of the effects of foot reflexology massage on vital signs and chemotherapy-induced anxiety in children with leukemia. Med-Surg Nursing J. 2016; 4(e68081).
  20. Jazayeri Z, Sajadi M, Dalvand H, et al. Comparison of the effect of foot reflexology and body massage on physiological indicators and bilirubin levels in neonates under phototherapy. Complement Ther Med. 2021; 59: 102684.
  21. Unesi Z, Izadpanah AM, Farajzadehe Z, et al. Impact of Distraction Technique on Reducing the Infants’ Vaccination Pain. Modern Care J. 2014; 11(1): 1–9.
  22. Beyer JE, Denyes MJ, Villarruel AM. The creation, validation, and continuing development of the Oucher: a measure of pain intensity in children. J Pediatr Nurs. 1992; 7(5): 335–346.
  23. Schulz KF, Altman DG, Moher D, et al. CONSORT Group. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. Trials. 2010; 11: 32.
  24. Hudson BF, Davidson J, Whiteley MS. The impact of hand reflexology on pain, anxiety and satisfaction during minimally invasive surgery under local anaesthetic: a randomised controlled trial. Int J Nurs Stud. 2015; 52(12): 1789–1797.
  25. Dolatian M, Hasanpour A, Heshmat R, et al. The effect of reflexology on pain intensity of labor. J Adv Med Biomed Res. 2010; 18(72): 52–61.
  26. Taha NM, Ali ZH. Effect of reflexology on pain and quality of life in a patient with rheumatoid arthritis. Marsland Press, Newburgh 2011: 357–365.
  27. Elsayed AE, Kandeel NA, El-Aziz WW. The Effect of Foot Reflexology on Physiological Indicators and Mechanical Ventilation Weaning Time among Open-Heart Surgery Patients. Am J Nurs Res. 2019; 7(4): 412–419.
  28. Shahsavari H, Abad M, Yekaninejad M. The effects of foot reflexology on anxiety and physiological parameters among candidates for bronchoscopy: A randomized controlled trial. Eur J Integrat Med. 2017; 12: 177–181.
  29. Sheikh S, Yaghoubinia F, Navidian A. Impact of Foot Reflexology Massage on the Patients’ Physiological Indicators without Trauma with Loss of Consciousness in the Intensive Care Unit. Indian J Publ Health Res Dev. 2017; 8(2): 201.
  30. Samadi N, Allahyari I, Mazaheri E, et al. Effect of foot reflexology on physiologic index of neonates. Iranian J Neonatol. 2014; 5(1): 19–22.
  31. Padial ER, López NT, Bujaldón JL, et al. Cardiovascular effects of reflexology in healthy individuals: evidence for a specific increase in blood pressure. Alternative Med Stud. 2012; 2(1): 4.
  32. Khazaei T, Rezaei Mo, Sebzari AR, et al. The effect of foot reflexology massage on the stress and neuropathic pain caused by chemotherapy in women with breast cancer and genitalia. J Birjand Univ Med Sci. 2019; 26(1): 4–12.



Reports of Practical Oncology and Radiotherapy