Palliative brachytherapy to axilla and hypopharynx in elderly patient with hypopharyngeal squamous cell carcinoma — case report
Abstract
Brachytherapy (BT) is an important local treatment of tumor and it can be applied to different anatomical sites either in a curative or palliative setting. BT can deliver large dose of radiation to the tumor while sparing the surrounding normal tissue which translates into a better therapeutic ratio compared to external beam radiotherapy. However, the evidence for the use of brachytherapy in the palliative setting is lacking in the literature. In this case report, we describe the brachytherapy technique and outcome of a patient with squamous cell carcinoma of the hypopharynx who underwent palliative brachytherapy to the hypopharynx and metastatic tumor at the right axilla.
Keywords: brachytherapyaxillahypopharynxelderlysquamous cell carcinoma
References
- Martin JM, Handorf EA, Kutikov A, et al. The rise and fall of prostate brachytherapy: use of brachytherapy for the treatment of localized prostate cancer in the National Cancer Data Base. Cancer. 2014; 120(14): 2114–2121.
- Gill BS, Lin JF, Krivak TC, et al. National Cancer Data Base analysis of radiation therapy consolidation modality for cervical cancer: the impact of new technological advancements. Int J Radiat Oncol Biol Phys. 2014; 90(5): 1083–1090.
- Homs MYV, Steyerberg EW, Eijkenboom WMH, et al. Single-dose brachytherapy versus metal stent placement for the palliation of dysphagia from oesophageal cancer: multicentre randomised trial. Lancet. 2004; 364(9444): 1497–1504.
- Skowronek J. Current status of brachytherapy in cancer treatment - short overview. J Contemp Brachytherapy. 2017; 9(6): 581–589.
- Skowronek J, Piotrowski T, Młynarczyk W, et al. Advanced tracheal carcinoma — a therapeutic significance of HDR brachytherapy in palliative treatment. Neoplasma. 2004; 51(4): 313–318.
- Hass P, Mohnike K, Kropf S, et al. Comparative analysis between interstitial brachytherapy and stereotactic body irradiation for local ablation in liver malignancies. Brachytherapy. 2019; 18(6): 823–828.
- Hayes JH, Ollendorf DA, Pearson SD, et al. Observation versus initial treatment for men with localized, low-risk prostate cancer: a cost-effectiveness analysis. Ann Intern Med. 2013; 158(12): 853–860.
- Marcrom SR, Kahn JM, Colbert LE, et al. Brachytherapy Training Survey of Radiation Oncology Residents. Int J Radiat Oncol Biol Phys. 2019; 103(3): 557–560.
- Syadwa AS, Anita ZB. Palliative radiotherapy for advanced Cancer: Are we giving it to the right patient at the right time? Med J Malaysia. 2018; 73(4): 190–196.
- Lutz ST, Chow EL, Hartsell WF, et al. A review of hypofractionated palliative radiotherapy. Cancer. 2007; 109(8): 1462–1470.
- Shasha D, Harrison LB. The role of brachytherapy for palliation. Semin Radiat Oncol. 2000; 10(3): 222–239.
- Bergquist H, Wenger U, Johnsson E, et al. Stent insertion or endoluminal brachytherapy as palliation of patients with advanced cancer of the esophagus and gastroesophageal junction. Results of a randomized, controlled clinical trial. Dis Esophagus. 2005; 18(3): 131–139.
- Fuccio L, Mandolesi D, Farioli A, et al. Brachytherapy for the palliation of dysphagia owing to esophageal cancer: A systematic review and meta-analysis of prospective studies. Radiother Oncol. 2017; 122(3): 332–339.
- Rühle A, Andratschke N, Siva S, et al. Is there a role for stereotactic radiotherapy in the treatment of renal cell carcinoma? Clin Transl Radiat Oncol. 2019; 18: 104–112.