Vol 9, No 2 (2023)
Review paper
Published online: 2023-06-15

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Everything you always wanted to know about systemic sclerosis but were afraid to ask: Part 1. Clinical pictures

Magdalena Kopeć-Mędrek12, Monika Bultrowicz2, Olga Gumkowska-Sroka3, Barbara Buc-Piorun2, Klaudia Palka2, Karolina Nowak2, Przemysław Kotyla132
Rheumatology Forum 2023;9(2):63-72.

Abstract

The authors present the clinical picture of systemic sclerosis including organ and system involvement.

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References

  1. Didier K, Robbins A, Antonicelli F, et al. Updates in systemic sclerosis pathogenesis: Toward new therapeutic opportunities [article in French]. Rev Med Interne. 2019; 40(10): 654–663.
  2. Avouac J, Fransen J, Walker UA, et al. Preliminary criteria for the very early diagnosis of systemic sclerosis: results of a Delphi Consensus Study from EULAR Scleroderma Trials and Research Group. Ann Rheum Dis. 2011; 70(3): 476–481.
  3. Wollheim FA. Classification of systemic sclerosis: vision and reality. Rheumatology (Oxford). 2005; 44(10): 1212–1216.
  4. van den Hoogen F, Khanna D, Fransen J, et al. 2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Arthritis Rheum. 2013; 65(11): 2737–2747.
  5. Sierakowski S, Sierakowska M. Twardzina układowa. In: Zimmermann-Górska I. ed. Reumatologia kliniczna. PZWL Wydawnictwo Lekarskie, Warszawa 2008: 603–605.
  6. Cutolo M. Atlas of capillaroscopy in rheumatic diseases. Elsevier 2010.
  7. Denton CP, Khanna D. Systemic sclerosis. Lancet. 2017; 390(10103): 1685–1699.
  8. Racine M, Hudson M, Baron M, et al. The impact of pain and itch on functioning and health-related quality of life in systemic sclerosis: an exploratory study. J Pain Symptom Manage. 2016; 52(1): 43–53.
  9. Medsger TA, Benedek TG. History of skin thickness assessment and the Rodnan skin thickness scoring method in systemic sclerosis. J Scleroderma Relat Disord. 2019; 4(2): 83–88.
  10. Jerjen R, Nikpour M, Krieg T, et al. Systemic sclerosis in adults. Part I: Clinical features and pathogenesis. J Am Acad Dermatol. 2022; 87(5): 937–954.
  11. Valido A, Cordeiro I. Calcinosis in systemic sclerosis. N Engl J Med. 2019; 381(17): 1663.
  12. Avouac J, Walker UA, Hachulla E, Riemekasten G, Cuomo G i wsp. EUSTAR.
  13. Siegert E, Uruha A, Goebel HH, et al. Systemic sclerosis-associated myositis features minimal inflammation and characteristic capillary pathology. Acta Neuropathol. 2021; 141(6): 917–927.
  14. Leurs A, Dubucquoi S, Machuron F, et al. Extended myositis-specific and -associated antibodies profile in systemic sclerosis: A cross-sectional study. Joint Bone Spine. 2021; 88(1): 105048.
  15. Cappelli S, Bellando Randone S, Camiciottoli G, et al. Interstitial lung disease in systemic sclerosis: where do we stand? Eur Respir Rev. 2015; 24(137): 411–419.
  16. Distler O, Assassi S, Cottin V, et al. Predictors of progression in systemic sclerosis patients with interstitial lung disease. Eur Respir J. 2020; 55(5): 1902026.
  17. Orlandi M, Meliante LA, Damiani A, et al. The role of bronchoalveolar lavage in systemic sclerosis interstitial lung disease: A systematic literature review. Pharmaceuticals (Basel). 2022; 15(12): 1584.
  18. Pugnet G, Marjanovic Z, Deligny C, et al. Reproducibility and utility of the 6-minute walk test in systemic sclerosis. J Rheumatol. 2018; 45(9): 1273–1280.
  19. Bruni C, Ross L. Cardiac involvement in systemic sclerosis: Getting to the heart of the matter. Best Pract Res Clin Rheumatol. 2021; 35(3): 101668.
  20. Alexander EL, Firestein GS, Weiss JL, et al. Reversible cold-induced abnormalities in myocardial perfusion and function in systemic sclerosis. Ann Intern Med. 1986; 105(5): 661–668.
  21. Allanore Y, Meune C, Kahan A. Systemic sclerosis and cardiac dysfunction: evolving concepts and diagnostic methodologies. Curr Opin Rheumatol. 2008; 20(6): 697–702.
  22. Ahmed Z, Saxena P. Effusive constrictive pericarditis in systemic sclerosis. Eur J Rheumatol. 2021; 8(1): 53–54.
  23. Hachulla AL, Launay D, Gaxotte V, et al. Cardiac magnetic resonance imaging in systemic sclerosis: a cross-sectional observational study of 52 patients. Ann Rheum Dis. 2009; 68(12): 1878–1884.
  24. Allanore Y, Komocsi A, Vettori S, et al. N-terminal pro-brain natriuretic peptide is a strong predictor of mortality in systemic sclerosis. Int J Cardiol. 2016; 223: 385–389.
  25. Lechartier B, Humbert M. Pulmonary arterial hypertension in systemic sclerosis. Presse Med. 2021; 50(1): 104062.
  26. Humbert M, Guignabert C, Bonnet S, et al. Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives. Eur Respir J. 2019; 53(1): 1801887.
  27. D'Alto M, Romeo E, Argiento P, et al. Accuracy and precision of echocardiography versus right heart catheterization for the assessment of pulmonary hypertension. Int J Cardiol. 2013; 168(4): 4058–4062.
  28. Frech TM, Mar D. Gastrointestinal and hepatic disease in systemic sclerosis. Rheum Dis Clin North Am. 2018; 44(1): 15–28.
  29. Hughes M, Ong VH, Anderson ME, et al. Consensus best practice pathway of the UK Scleroderma Study Group: digital vasculopathy in systemic sclerosis. Rheumatology (Oxford). 2015; 54(11): 2015–2024.
  30. Ingraham KM, O'Brien MS, Shenin M, et al. Gastric antral vascular ectasia in systemic sclerosis: demographics and disease predictors. J Rheumatol. 2010; 37(3): 603–607.
  31. Marie I, Ducrotté P, Denis P, et al. Outcome of small-bowel motor impairment in systemic sclerosis--a prospective manometric 5-yr follow-up. Rheumatology (Oxford). 2007; 46(1): 150–153.
  32. Assassi S, Fritzler MJ, Arnett FC, et al. Primary biliary cirrhosis (PBC), PBC autoantibodies, and hepatic parameter abnormalities in a large population of systemic sclerosis patients. J Rheumatol. 2009; 36(10): 2250–2256.
  33. Chrabaszcz M, Małyszko J, Sikora M, et al. Renal involvement in systemic sclerosis: an update. Kidney Blood Press Res. 2020; 45(4): 532–548.
  34. Wielosz E. Zajęcie nerek w twardzinie układowej. Przegląd Reumatologiczny. 2008; 1(19): 3–4.
  35. Bütikofer L, Varisco PA, Distler O, et al. ACE inhibitors in SSc patients display a risk factor for scleroderma renal crisis-a EUSTAR analysis. Arthritis Res Ther. 2020; 22(1): 59.