Vol 8, No 2 (2022)
Review paper
Published online: 2022-06-23
Risk of cancers in polymyositis and dermatomyositis
DOI: 10.5603/RF.2022.0008
Rheumatology Forum 2022;8(2):69-76.
Abstract
Idiopathic inflammatory myopathy (IIM) is a rare autoimmune disease that women are more often diagnosed. The most common IIM are polymyositis (PM) and dermatomyositis (DM). More often than in other rheumatic diseases, various neoplasms develop in their course (CAM, cancer-associated myositis). The most common cancers included ovarian and reproductive organs cancer, breast, lung, gastrointestinal and hematopoietic cancer (mainly non-Hodgkin’s lymphomas), melanoma, and nasopharyngeal cancer (the last one is widespread in Southeast Asia). It is worth emphasizing that a neoplastic disease may develop in IIM, and IIM may be a factor influencing the initiation of carcinogenic processes. The presented manuscript discusses the symptoms occurring in their course CAM and the risk factors for cancer development in detail. The importance of clinical observation of patients with PM/DM and the necessity of quick oncological diagnostics in the case of suspicion of such a process was discussed and emphasized (including the importance of screening tests).
Keywords: polymyositisdermatomyositiscancer riskdiagnosis
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