Vol 18, No 2 (2021)
Research paper
Published online: 2021-03-25
Get Citation

Effects of depressive and anxiety disorders during pregnancy on gestational age and birth weight: A case-control study

Soraia Antunes Ribeiro, Daniela Agostinho David, Ilda Vieira Murta, João Mariano Marques, Vítor Daniel Vaz, Carla Santos Silva
DOI: 10.5603/PSYCH.2021.0014
·
Psychiatria 2021;18(2):88-91.

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Vol 18, No 2 (2021)
Prace oryginalne - nadesłane
Published online: 2021-03-25

Abstract

Introduction: Depression and anxiety are the most common psychiatric disorders during pregnancy. Several
studies suggest that maternal affective state can negatively affect the fetus, leading to worst neonatal outcomes.
The aim of this study was to compare the frequency of preterm birth (PTB), low birth weight (LBW), lower 1- and
5-minute Apgar scores and admission to neonatal intensive care unit between newborns of women with anxiety/
/depressive disorders and those of women without mental illness.

Material and methods: It was performed a retrospective case-control study with 78 women with anxiety, depression
or both, who were followed in Liaison Psychiatry during pregnancy and gave birth between October
2018 and October 2019. The control group was a random sample of women without mental illness who gave
birth in the same period and institution.

Results: A statistically significant difference (p = 0.039, OR = 2.68) was observed between the frequency of
LBW in the newborns of participants (n = 8, 10.26%) and in those of control group (n = 11, 3.83%). The same
was observed in the mean of birth weight (p = 0.008) and the frequency of admission to neonatal intensive care
unit (p = 0.000, OR = 14.05).

Conclusions: This study showed negative effects of maternal depressive and anxiety disorders in birth weight
and admission to neonatal intensive care unit

Abstract

Introduction: Depression and anxiety are the most common psychiatric disorders during pregnancy. Several
studies suggest that maternal affective state can negatively affect the fetus, leading to worst neonatal outcomes.
The aim of this study was to compare the frequency of preterm birth (PTB), low birth weight (LBW), lower 1- and
5-minute Apgar scores and admission to neonatal intensive care unit between newborns of women with anxiety/
/depressive disorders and those of women without mental illness.

Material and methods: It was performed a retrospective case-control study with 78 women with anxiety, depression
or both, who were followed in Liaison Psychiatry during pregnancy and gave birth between October
2018 and October 2019. The control group was a random sample of women without mental illness who gave
birth in the same period and institution.

Results: A statistically significant difference (p = 0.039, OR = 2.68) was observed between the frequency of
LBW in the newborns of participants (n = 8, 10.26%) and in those of control group (n = 11, 3.83%). The same
was observed in the mean of birth weight (p = 0.008) and the frequency of admission to neonatal intensive care
unit (p = 0.000, OR = 14.05).

Conclusions: This study showed negative effects of maternal depressive and anxiety disorders in birth weight
and admission to neonatal intensive care unit

Get Citation

Keywords

anxiety disorders, depression, pregnancy, infant, newborn

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About this article
Title

Effects of depressive and anxiety disorders during pregnancy on gestational age and birth weight: A case-control study

Journal

Psychiatria (Psychiatry)

Issue

Vol 18, No 2 (2021)

Article type

Research paper

Pages

88-91

Published online

2021-03-25

DOI

10.5603/PSYCH.2021.0014

Bibliographic record

Psychiatria 2021;18(2):88-91.

Keywords

anxiety disorders
depression
pregnancy
infant
newborn

Authors

Soraia Antunes Ribeiro
Daniela Agostinho David
Ilda Vieira Murta
João Mariano Marques
Vítor Daniel Vaz
Carla Santos Silva

References (15)
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  10. Cutland CL, Lackritz EM, Mallett-Moore T, et al. Brighton Collaboration Low Birth Weight Working Group. Low birth weight: Case definition & guidelines for data collection, analysis, and presentation of maternal immunization safety data. Vaccine. 2017; 35(48 Pt A): 6492–6500.
  11. Cnattingius S, Norman M, Granath F, et al. Apgar Score Components at 5 Minutes: Risks and Prediction of Neonatal Mortality. Paediatr Perinat Epidemiol. 2017; 31(4): 328–337.
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