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Vol 17, No 3 (2020)
Review paper
Published online: 2020-08-30

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Citalopram: an SSRI antidepressant that has been rediscovered

Andrzej Czernikiewicz, Tomasz Horoch
Psychiatria 2020;17(3):130-133.


Citalopram is the most selective molecule in the class of selective serotonin reuptake inhibitors (SSRIs), except its active
enantiomer S-citalopram. It belongs to the group of antidepressant and anxiolytic drugs, which is currently the standard
in the treatment of depressive disorders and anxiety disorders with panic attacks, especially for the elderly. There is
a lower risk of adverse interactions with other drugs because citalopram is metabolized by several CYP isoenzymes.
The risk of sexual dysfunction caused by citalopram appears to be relatively smaller in comparison with other SSRIs.

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