Vol 82, No 6 (2024)
Clinical vignette
Published online: 2024-05-15

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CLINICAL VIGNETTE

Peak frequency analysis and differentiation between near-field and far-field electrograms of the ventricular tachycardia circuit leads to successful ablation of arrhythmia

Jakub Malinowski12Jan Ciszewski3Mariusz Pytkowski3Aleksander Maciąg3
1Faculty of Medicine, Medical University of Warsaw, Warszawa, Poland
2Students’ Scientific Society affiliated at National Institute of Cardiology, Warszawa, Poland
32nd Department of Arrhythmia, National Institute of Cardiology, Warszawa, Poland

Correspondence to:

Aleksander Maciąg, MD, PhD,

Cardinal Stefan Wyszynski National Institute of Cardiology,

Alpejska 42, 04–628 Warszawa, Poland,

phone: +48 502 249 545,

e-mail: amaciag@ikard.pl

Copyright by the Author(s), 2024

DOI: 10.33963/v.phj.100569

Received: February 29, 2024

Accepted: May 5, 2024

Early publication date: May 15, 2024

Achieving the subepicardial substrate of ventricular tachycardia (VT) during endocardial mapping can be challenging, particularly in the low-amplitude area [1, 2]. Multipolar electrodes and omnipolar technology allow the mapping of even small areas of electrically active tissue, particularly in the region of the post-infarction scar; they also provide a wealth of information useful for visualizing the arrhythmia substrate [3]. EnSite OT Near Field (Abbott Chicago, IL, US) is a complementary technology that enables distinction between near-field and far-field potentials of intracar­diac electrograms in electroanatomic mapping. It facilitates differentiation of the arrhythmia substrate component from irrelevant signal elements [4].

We present the case of a 64-year-old man with a history of electrical storm, left ventricular (LV) inferior wall myocardial infarction, heart failure with reduced ejection fraction of ~30%, stable coronary artery disease, and an implantable cardioverter-defibrillator implanted for secondary prevention, who was admitted to the cardiac arrhythmia unit for recurrent ventricular tachyarrhythmias with a rate below implantable cardioverter-defibrillator detection. The patient was qualified for catheter ablation of underlying VT.

The patient was connected to an intracardiac recording system (Bard US) and an Ensite X electroanatomic system (Abbott). Decapolar and quadripolar diagnostic catheters were placed in the coronary sinus and His bundle area, respectively, via the right femoral approach. An Advisor HD Grid Mapping Catheter and subsequent Tacti Cath ablation catheter (both Abbott) were introduced into the LV via transseptal puncture. Clinical VT with a cycle of approximately 530 ms was easily induced during the electrophysiological study. Endocardial mapping of the LV was performed du- ring the hemodynamically well-tolerated VT. A large post-infarction scar was visualized in the inferior-posterior part of the left ventricle. Despite using the multipolar catheter and the omnipolar technology, only the entry and exit tachycardia areas could be visualized on the propagation map while the critical tachycardia isthmus was not visible.

During the entrainment, it was possible to locate the areas close to the VT exit with up to 79% pace mapping and a postpacing interval (PPI) minus tachycardia cycle length (TCL) of around 44 ms. The EnSite OT near-field technology was then used, with peak frequency (PF) recorded signals set at 2501000 Hz, to distinguish the near-field from the far-field components and to analyze the low-field region, allowing areas associated with VT conduction to be identified (Figure 1).

Figure 1. Sites of tachycardia interruption. A. IEGM recordings. Entraiment in application site near tachycardia exit. Pace mapping of tachycardia morphology 79% PPI TCL +44 ms. B. Moment of final VT interruption. C. Propagation map showing VT circle on left ventricular inferior wall with arrhythmia interruption site marked (red arrow) note that only half of circle was visible. D. Potential map with peak frequency analysis filter overlay highlighting area of interest in the scar

PF analysis of the fragmented potentials allowed selection of the site for further radio­frequency (RF) energy application. Possible modification of a part of the tachycardia circuit led to VT termination during RF application, probably with transmural application near the exit site. Clinical ventricular tachycardia was no longer induced during electrophysiological study after ablation.

The case presented here illustrates the potential benefits of using the PF tool as an adjunct to multipole mapping and entrainment [5]. Although this method does not replace existing methods, it may reduce the risk of unnecessary applications at sites where far-field signals are present and may distinguish the correct fragmented potential as part of the arrhythmoge­nic substrate.

Article information

Conflict of interest: None declared.

Funding: None.

Open access: This article is available in open access under Creative Common Attribution-Non-Commercial-No Derivatives 4.0 International (CC BY-NC-ND 4.0) license, which allows downloading and sharing articles with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially. For commercial use, please contact the journal office at polishheartjournal@ptkardio.pl

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