Tom 1, Nr 1 (2024)
Artykuł przeglądowy
Opublikowany online: 2024-06-21
Wyświetlenia strony
25
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0
Nabłonek dróg oddechowych w przewlekłej obturacyjnej chorobie płuc — struktura, funkcja i dysfunkcja
1
DOI: 10.5603/pp.99671
Pneum Pol 2024;1(1):1-9.
Streszczenie
Nabłonek dróg oddechowych dróg oddechowych przechodzi poważne zmiany strukturalne i czynnościowe wskutek działania zewnętrznych bodźców fizycznych, chemicznych i alergizujących. Komórki podstawne stanowią nie tylko element stałej struktury o istotnym znaczeniu czynnościowym, ale pełnią rolę progenitora w odnowie nabłonka zarówno w zdrowiu, jak i w chorobie. W pracy omówiono te następstwa pobudzenia komórek, które z jednej strony wydają się mieć istotne znaczenie dla klinicysty, z drugiej stanowią przedmiot poszukiwań terapeutycznych.
Słowa kluczowe: rola komórekstruktutra EMTkostykosteroidystatyny
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