Manifestacje płucne ANCA-zależnych zapaleń naczyń
Streszczenie
Manifestacje płucne są jedną z najczęstszych manifestacji ANCA-zależnych zapaleń naczyń (ANCA, antineutral cytoplasmic antibody). Do tej grupy chorób należy ziarniniakowatość z zapaleniem naczyń (GPA, granulomatosis with poliangitis), mikroskopowe zapalenie naczyń (MPA, microscopic polyangitis), eozynofilowa ziarniniakowatość z zapaleniem naczyń (EGPA, eosinophilic granulomatosis with polyangitis). W tej pracy przedstawiamy 5 najczęstszych manifestacji płucnych: 1) guzki, jamki, nacieki 2) owrzodzenia błony śluzowej tchawicy lub oskrzeli 3) krwawienie wewnątrzpęcherzykowe, 4) chorobę śródmiąższową płuc 5) astmę — ich diagnostykę różnicową, leczenie oraz powikłania w świetle najnowszych badań oraz nowych wytycznych leczenia opublikowanych przez amerykańskie oraz europejskie towarzystwa naukowe (ACR, American College of Reumatology oraz EULAR, European Alliance of Associations for Rheumatology).
Słowa kluczowe: zależne zapalenia naczyńziarniniakowatość z zapaleniem naczyń (GPA)mikroskopowe zapalenie naczyńeozynofilowa ziarniniakowatość z zapaleniem naczyńguzkiowrzodzenia błony śluzowejkrwawienie wewnątrzpęcherzykowechoroba śródmiąższowa płucastma
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