Vol 6 (2021): Continuous Publishing
Case report
Published online: 2021-10-27

open access

Page views 5972
Article views/downloads 311
Get Citation

Connect on Social Media

Connect on Social Media

Swept-source optical coherence tomography angiography findings in a patient with Behçet’s disease: a case report

Diego Bueso-Ponce1, Nicolás Rivera-Valdivia1, Carlos Salgado-Cerrate1, Pablo Cabal-López1, Hiroshi Maeda-Yasunaga1, Carlos Abdala-Caballero2
Ophthalmol J 2021;6:193-198.

Abstract

We present the clinical case of a 28-year-old female patient with a diagnosis of Behçet’s disease and unilateral relapsing ocular involvement in systemic management with infliximab. Optical coherence tomography angiography with swept-source technology (DRI OCT Triton Plus™, Topcon Corporation, Tokyo, Japan) revealed asymmetric compromise between both eyes. Decreased foveal vascular density, asymmetrical foveal avascular zone enlargement at superficial and deep capillary plexuses, and focal areas of hypoperfusion at the deep capillary plexus around the macula with corresponding hyporreflective lesions in the en face slab in the left eye were noted.

Swept-source OCT angiography (SS-OCTA) helped identify early asymmetrical microvascular structural alterations compatible with macular ischemia in a patient with systemic manifestations and unilateral ocular compromise.

Article available in PDF format

View PDF Download PDF file

References

  1. Zeidan MJ, Saadoun D, Garrido M, et al. Behçet's disease physiopathology: a contemporary review. Auto Immun Highlights. 2016; 7(1): 4.
  2. Paovic J, Paovic P, Sredovic V, et al. Correlation between Ocular Manifestations and Their Complications as Opposed to Visual Acuity and Treatment in Behcet's Disease. Autoimmune Dis. 2013; 2013: 842673.
  3. Hatemi G, Christensen R, Bang D, et al. 2018 update of the EULAR recommendations for the management of Behçet's syndrome. Ann Rheum Dis. 2018; 77(6): 808–818.
  4. Somkijrungroj T, Vongkulsiri S, Kongwattananon W, et al. Assessment of Vascular Change Using Swept-Source Optical Coherence Tomography Angiography: A New Theory Explains Central Visual Loss in Behcet's Disease. J Ophthalmol. 2017; 2017: 2180723.
  5. Calamia KT, Wilson FC, Icen M, et al. Epidemiology and clinical characteristics of Behçet's disease in the US: a population-based study. Arthritis Rheum. 2009; 61(5): 600–604.
  6. Hussein MA, Eissa IM, Dahab AA. Vision-Threatening Behcet's Disease: Severity of Ocular Involvement Predictors. J Ophthalmol. 2018; 2018: 9518065.
  7. Khairallah M, Abroug N, Khochtali S, et al. Optical coherence tomography angiography in patients witj Behcet uveitis. Retina. 2017; 37(9): 1678–1691.
  8. Emre S, Güven-Yılmaz S, Ulusoy MO, et al. Optical coherence tomography angiography findings in Behcet patients. Int Ophthalmol. 2019; 39(10): 2391–2399.
  9. Raafat KA, Allam RS, Medhat BM. Optical coherence tomography angiography findings in patients with nonocular Behcet disease. Retina. 2019; 39(8): 1607–1612.
  10. Türkcü FM, Şahin A, Karaalp Ü, et al. Automated quantification of foveal avascular zone and vascular density in Behçet's disease. Ir J Med Sci. 2020; 189(1): 349–354.
  11. Silva D, Lopes A, Colaço L, et al. Optical coherence tomography with angiography in Behcet Uveitis. Vision Pan-America, The Pan-American Journal of Ophthalmology. 2018; 17(3): 59–66.
  12. Goker YS, Yılmaz S, Kızıltoprak H, et al. Quantitative Analysis of Optical Coherence Tomography Angiography Features in Patients with Nonocular Behcet's Disease. Curr Eye Res. 2019; 44(2): 212–218.
  13. Çömez A, Beyoğlu A, Karaküçük Y. Quantitative analysis of retinal microcirculation in optical coherence tomography angiography in cases with Behçet's disease without ocular involvement. Int Ophthalmol. 2019; 39(10): 2213–2221.
  14. de Carlo TE, Romano A, Waheed NK, et al. A review of optical coherence tomography angiography (OCTA). Int J Retina Vitreous. 2015; 1: 5.
  15. Gao SS, Jia Y, Zhang M, et al. Optical Coherence Tomography Angiography. Invest Ophthalmol Vis Sci. 2016; 57(9): OCT27–OCT36.