Blood cell ratios in patients with primary acquired nasolacrimal duct obstruction
Abstract
Background: In this study, we aimed to measure neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and mean platelet volume (MPV) levels in primary acquired nasolacrimal duct obstruction (PANDO) patients and to determine whether there it could be used as a marker for PANDO. Material and methods: This retrospective study included 61 patients with PANDO and 65 healthy controls. Data were excluded from the file records of patients who underwent external dacryocystorhinostomy (DCR). Blood samples were obtained from venous blood and serum neutrophil, lymphocyte, and platelet data of all patients were recorded and also, NLR-PLR values were calculated. Results: There was no significant difference between PANDOs and controls in terms of gender and age (p > 0.05). Neutrophil-to-lymphocyte was significantly increased in PANDOs compared to the controls (p < 0.05). There was no statistically significant difference between PANDOs and controls in term of PLR (p > 0.05). The average MPV in the PANDOs was found to be significantly lower than controls (p < 0.05). Conclusion: Neutrophil-to-lymphocyte ratio and MPV counts were associated with PANDO.
Keywords: neutrophil-to-lymphocyte ratioplatelet-to-lymphocyte ratiomean platelet volumeprimary acquired nasolacrimal duct obstruction
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