Vol 4 (2019): Continuous Publishing
Case report
Published online: 2019-05-21
Autosomal dominant neovascular inflammatory vitreoretinopathy — a case series
DOI: 10.5603/OJ.2019.0003
Ophthalmol J 2019;4:31-39.
Abstract
The objective of our study was to report the course of the disease in a family affected with autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV, OMIM#193235). ADNIV is a very rare inherited blinding disease due to mutations in CAPN5 gene. We assembled a retrospective observational case series of ADNIV patients. We noticed first symptoms in different ages, similar course of the disease and its progression leading in most cases to complete blindness despite treatment.
Keywords: autosomal dominant neovascular inflammatory vitreoretinopathyADNIVuveitisneovascularizationproliferative vitreoretinopathycystoid macular edemaCAPN5calpain-5
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