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Vol 2, No 1 (2017)
REVIEW
Published online: 2017-03-22
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Blepharitis and Demodex spp. infection

Karolina Kot, Maciej Czepita, Danuta Kosik-Bogacka, Natalia Łanocha-Arendarczyk, Damian Czepita
DOI: 10.5603/OJ.2017.0006
·
Ophthalmol J 2017;2(1):22-27.

open access

Vol 2, No 1 (2017)
REVIEW
Published online: 2017-03-22

Abstract

According to the latest reports Demodex mites appear to play an important role in the pathogenesis of chronic blepharitis. Demodex mites are cosmopolitan and are present in many species of mammals. In this paper we describe two species that are found in humans: Demodex folliculorum and D. brevis. Infection occurs during direct contact with an affected person and also through contact with dust containing eggs of the parasite, through contact with bed linen, as well as cosmetics used together with an affected person. Treatment of chronic blepharitis caused by D. folliculorum and D. brevis is difficult and time consuming. Some improvement can be achieved after topical application of yellow mercury ointment, sulphuric ointment, camphor oil, crotamiton, cholinesterase inhibitors, sulfacetamide, steroids, antibiotics and antifungal drugs. Good results have been achieved with oral ivermectin and permethrin cream. However, the best results were observed after treatment with metronidazole.  

Abstract

According to the latest reports Demodex mites appear to play an important role in the pathogenesis of chronic blepharitis. Demodex mites are cosmopolitan and are present in many species of mammals. In this paper we describe two species that are found in humans: Demodex folliculorum and D. brevis. Infection occurs during direct contact with an affected person and also through contact with dust containing eggs of the parasite, through contact with bed linen, as well as cosmetics used together with an affected person. Treatment of chronic blepharitis caused by D. folliculorum and D. brevis is difficult and time consuming. Some improvement can be achieved after topical application of yellow mercury ointment, sulphuric ointment, camphor oil, crotamiton, cholinesterase inhibitors, sulfacetamide, steroids, antibiotics and antifungal drugs. Good results have been achieved with oral ivermectin and permethrin cream. However, the best results were observed after treatment with metronidazole.  

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Keywords

pathogenesis, infection, ocular demodicosis, treatment

About this article
Title

Blepharitis and Demodex spp. infection

Journal

Ophthalmology Journal

Issue

Vol 2, No 1 (2017)

Pages

22-27

Published online

2017-03-22

DOI

10.5603/OJ.2017.0006

Bibliographic record

Ophthalmol J 2017;2(1):22-27.

Keywords

pathogenesis
infection
ocular demodicosis
treatment

Authors

Karolina Kot
Maciej Czepita
Danuta Kosik-Bogacka
Natalia Łanocha-Arendarczyk
Damian Czepita

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