open access
Randomized clinical studies — science, belief or advertisement only
Affiliations- Retired doctor, Lawendowa, 45-470 Opole, Poland
open access
Abstract
The results of randomized clinical studies are important in evaluation of drugs’ or medical procedures’ efficacy. Statistical analyses are meaningful in publications and conference presentations. This paper discusses the role and value of selected statistical methods. It is clear that in clinical studies patients and time to event (recognized as end study point) are essential. According to that the question arises — do all these statistical analyses are important or do they play only a role in drug promotion.
Abstract
The results of randomized clinical studies are important in evaluation of drugs’ or medical procedures’ efficacy. Statistical analyses are meaningful in publications and conference presentations. This paper discusses the role and value of selected statistical methods. It is clear that in clinical studies patients and time to event (recognized as end study point) are essential. According to that the question arises — do all these statistical analyses are important or do they play only a role in drug promotion.
Keywords
clinical studies; statistical analyses
About this articleTitle
Randomized clinical studies — science, belief or advertisement only
Journal
Issue
Article type
Review paper
Pages
133-139
Published online
2020-07-08
Page views
285
Article views/downloads
316
DOI
10.5603/OCP.2020.0022
Bibliographic record
Oncol Clin Pract 2020;16(3):133-139.
Keywords
clinical studies
statistical analyses
Authors
Kazimierz Drosik
References (3)- Kaplan EL, Meier P, Nonparametric estimation from incomplete observation. Journal of the American Statistical Association. 1958; 53(282): 457–481 (dostępny: https://web.stanford.edu/~lutian/coursepdf/KMpaper.pdf).
- Green S, Benedetti J, Crowley J. Clinical trials in oncology second edition. Chapman and Hall/CRC. Boca Raton, London, New York, Washington DC. 2003: 30–37.
- Green S, Benedetti J, Crowley J. Clinical trials in oncology second edition. Chapman and Hall/CRC. Boca Raton, London, New York, Washington DC. 2003: 37–39.