Vol 14, No 5 (2018)
Case report
Published online: 2019-02-15
Tracheal cancer in a 25-year-old woman — diagnostic difficulties
Oncol Clin Pract 2018;14(5):286-289.
Abstract
Tracheal cancers, in particular adenoid cystic carcinoma, are rare, hence the lack of unambiguous guidelines for
diagnostic and therapeutic procedures. The article presents the case of a 25-year-old woman diagnosed at the
stage of local advancement, after 2 years of treatment of misdiagnosed bronchial asthma. The patient underwent
surgical treatment, which turned out to be non-radical microscopically. The decision to use postoperative radiotherapy
was based on the estimated recurrence risk.
Keywords: tracheal canceradenoid cystic carcinomapostoperative radiotherapybronchial asthma
References
- Chang CY, Cheng SL, Chang SC. Adenoid cystic carcinoma of trachea treated with tumor curettage and adjuvant intensity modulated radiation therapy. South Med J. 2011; 104(1): 68–70.
- Regnard JF, Fourquier P, Levasseur P. Results and prognostic factors in resections of primary tracheal tumors: a multicenter retrospective study. The French Society of Cardiovascular Surgery. J Thorac Cardiovasc Surg. 1996; 111(4): 808–13; discussion 813.
- Yamamoto Y, Wistuba II, Kishimoto Y, et al. DNA analysis at p53 locus in adenoid cystic carcinoma: comparison of molecular study and p53 immunostaining. Pathol Int. 1998; 48(4): 273–280.
- Kim B. Palliative radiotherapy in a patient with pulmonary adenoid cystic carcinoma. Cancer Res Treat. 2007; 39(4): 185–188.
- Chargari C, Riet F, Mazevet M, et al. Complications of thoracic radiotherapy. Presse Med. 2013; 42(9 Pt 2): e342–e351.
- Maziak D, Todd T, Keshavjee S, et al. Adenoid cystic carcinoma of the airway: Thirty-two-year experience. The Journal of Thoracic and Cardiovascular Surgery. 1996; 112(6): 1522–1532.
- Honings J, Gaissert HA, Weinberg AC, et al. Prognostic value of pathologic characteristics and resection margins in tracheal adenoid cystic carcinoma. Eur J Cardiothorac Surg. 2010; 37(6): 1438–1444.
- Kanematsu T, Yohena T, Uehara T, et al. Treatment outcome of resected and nonresected primary adenoid cystic carcinoma of the lung. Ann Thorac Cardiovasc Surg. 2002; 8(2): 74–77.
- Webb BD, Walsh GL, Roberts DB, et al. Primary tracheal malignant neoplasms: the University of Texas MD Anderson Cancer Center experience. J Am Coll Surg. 2006; 202(2): 237–246.
- Shimizu J, Oda M, Matsumoto I, et al. Clinicopathological study of surgically treated cases of tracheobronchial adenoid cystic carcinoma. Gen Thorac Cardiovasc Surg. 2010; 58(2): 82–86.
- Junker K. Pathology of tracheal tumors. Thorac Surg Clin. 2014; 24(1): 7–11.
- Macchiarini P. Primary tracheal tumours. Lancet Oncol. 2006; 7(1): 83–91.
- Samant S, van den Brekel MW, Kies MS, et al. Concurrent chemoradiation for adenoid cystic carcinoma of the head and neck. Head Neck. 2012; 34(9): 1263–1268.
- Mornex F, Coquard R, Danhier S, et al. Role of radiation therapy in the treatment of primary tracheal carcinoma. Int J Radiat Oncol Biol Phys. 1998; 41(2): 299–305.
- Napieralska A, Miszczyk L, Blamek S. Tracheal cancer - treatment results, prognostic factors and incidence of other neoplasms. Radiol Oncol. 2016; 50(4): 409–417.
- Marks LB, Yorke ED, Jackson A, et al. Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys. 2010; 76(3 Suppl): S10–S19.
- Papaspyrou G, Hoch S, Rinaldo A, et al. Chemotherapy and targeted therapy in adenoid cystic carcinoma of the head and neck: a review. Head Neck. 2011; 33(6): 905–911.
- Laurie SA, Ho AL, Fury MG, et al. Systemic therapy in the management of metastatic or locally recurrent adenoid cystic carcinoma of the salivary glands: a systematic review. Lancet Oncol. 2011; 12(8): 815–824.