Vol 14, No 3 (2018)
Case report
Published online: 2018-06-21
A case of B-cell lymphoma of the uterus
DOI: 10.5603/OCP.2018.0022
Oncol Clin Pract 2018;14(3):164-166.
Abstract
Primary malignant lymphoma occurs rarely in the female reproductive tract. A case of a 64-year-old female patient diagnosed with B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma (B-UCL) of the uterus is presented. The patient underwent three cycles of chemotherapy based on R-CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisolone combined with rituximab), radiation therapy to the pelvis, and extended hysterectomy. The follow-up has been conducted for three years. No sign of disease recurrence has been observed in physical examination and on images.
Keywords: uterusB-cell lymphomaBurkitt lymphomaunclassifiable B-cell lymphomaprimary malignant lymphoma
References
- Vang R, Medeiros LJ, Ha CS, et al. Non-Hodgkin's lymphomas involving the uterus: a clinicopathologic analysis of 26 cases. Mod Pathol. 2000; 13(1): 19–28.
- Okuda T, Ijichil S, Yamashita S, et al. Diagnostic usefulness of FDG-PET/CT in advanced malignant lymphoma of the uterus: report of two cases. Eur J Gynaecol Oncol. 2015; 36(6): 737–741.
- Mandato VD, Palermo R, Falbo A, et al. Primary diffuse large B-cell lymphoma of the uterus: case report and review. Anticancer Res. 2014; 34(8): 4377–4390.
- Samama M, van Poelgeest M. Primary malignant lymphoma of the uterus: a case report and review of the literature. Case Rep Oncol. 2011; 4(3): 560–563.
- Swerdlow SH, Campo E, Pileri SA, et al. The 2016 revision of the World Health Organization classification of lymphoid neoplasms. Blood. 2016; 127(20): 2375–2390.
- Stroh EL, Besa PC, Cox JD, et al. Treatment of patients with lymphomas of the uterus or cervix with combination chemotherapy and radiation therapy. Cancer. 1995; 75(9): 2392–2399, doi: 10.1002/1097-0142(19950501)75:9<2392::aid-cncr2820750932>3.0.co;2-y.
- Cubo AM, Soto ZM, Cruz MÁ, et al. Primary diffuse large B cell lymphoma of the uterine cervix successfully treated by combined chemotherapy alone: A case report. Medicine (Baltimore). 2017; 96(19): e6846.
- Hashimoto A, Fujimi A, Kanisawa Y, et al. [Primary diffuse large B-cell lymphoma of the uterine cervix successfully treated with rituximabplus cyclophosphamide, doxorubicin, vincristine, and prednisone chemotherapy-a case report]. Gan To Kagaku Ryoho. 2013; 40(13): 2589–2592.
- Sharma V, Dora T, Patel M, et al. Case Report of Diffuse Large B Cell Lymphoma of Uterine Cervix Treated at a Semiurban Cancer Centre in North India. Case Rep Hematol. 2016; 2016: 3042531.
- Perry AM, Crockett D, Dave BJ, et al. B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and burkitt lymphoma: study of 39 cases. Br J Haematol. 2013; 162(1): 40–49.
- Zhao L, Ma Q, Wang Q, et al. Primary diffuse large B cell lymphoma arising from a leiomyoma of the uterine corpus. Diagn Pathol. 2016; 11: 9.
- Bürgesser MV, Gualco G, Diller A, et al. Clinicopathological features of aggressive B-cell lymphomas including B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell and Burkitt lymphomas: a study of 44 patients from Argentina. Ann Diagn Pathol. 2013; 17(3): 250–255.
- Baryakh EA, Misyurina AE, Kovrigina AM, et al. [Diagnosis and treatment in patients with B-cell lymphoma unclassified that is intermediate between diffuse large B-cell lymphoma and Burkitt's lymphoma]. Ter Arkh. 2015; 87(8): 77–85.
- Yahalom J, Illidge T, Specht L, et al. International Lymphoma Radiation Oncology Group. Modern radiation therapy for extranodal lymphomas: field and dose guidelines from the International Lymphoma Radiation Oncology Group. Int J Radiat Oncol Biol Phys. 2015; 92(1): 11–31.