open access

Vol 1, No 4 (2005)
Review paper
Published online: 2005-12-12
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Clinical significance of cancer related anaemia

Beata Ostrowska, Jan Walewski
Onkol. Prak. Klin 2005;1(4):201-210.

open access

Vol 1, No 4 (2005)
REVIEW ARTICLES
Published online: 2005-12-12

Abstract

Cancer related anaemia does have an unfauvorable impact on the functional capacity of the relevant tissue and organs. Anaemia and hypoxia worsen patient’s physical condition. The diminished capacity for physical activity has a detrimental impact on quality of life as it influenced a mental status, weaken cognitive function and lead to isolation and dicline their socioeconomic status. Anaemia causing tumour hypoxia leads to tumour progression through the increase of local tumour expansion and spreading of metastases. Tumour hypoxia directly or indirectly confer resistance to irradiation, some chemotherapeutic drugs, and photodynamic therapy. Better oxygenation can result in significant improvement of tumour response to treatment. Clinical evidence supports the need to closely monitor Hb level in cancer patients and anaemia should be corrected in order to improve chemo- and radiosensitivity and the quality of life.

Abstract

Cancer related anaemia does have an unfauvorable impact on the functional capacity of the relevant tissue and organs. Anaemia and hypoxia worsen patient’s physical condition. The diminished capacity for physical activity has a detrimental impact on quality of life as it influenced a mental status, weaken cognitive function and lead to isolation and dicline their socioeconomic status. Anaemia causing tumour hypoxia leads to tumour progression through the increase of local tumour expansion and spreading of metastases. Tumour hypoxia directly or indirectly confer resistance to irradiation, some chemotherapeutic drugs, and photodynamic therapy. Better oxygenation can result in significant improvement of tumour response to treatment. Clinical evidence supports the need to closely monitor Hb level in cancer patients and anaemia should be corrected in order to improve chemo- and radiosensitivity and the quality of life.
Get Citation

Keywords

symptoms of anaemia; tumour hypoxia; cancer resistance to therapy; anaemia correction

About this article
Title

Clinical significance of cancer related anaemia

Journal

Oncology in Clinical Practice

Issue

Vol 1, No 4 (2005)

Article type

Review paper

Pages

201-210

Published online

2005-12-12

Bibliographic record

Onkol. Prak. Klin 2005;1(4):201-210.

Keywords

symptoms of anaemia
tumour hypoxia
cancer resistance to therapy
anaemia correction

Authors

Beata Ostrowska
Jan Walewski

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