Vol 2, No 2 (2006)
Review paper
Published online: 2006-05-04
Glioblastoma multiforme: impasse or progress in post-operative adjuvant therapy
Onkol. Prak. Klin 2006;2(2):59-63.
Abstract
Two methods of systemic treatment of patients with newly diagnosed glioblastoma are presented: nitrosourea-
based adjuvant chemotherapy, and irradiation plus concomitant and adjuvant temozolomide.
The second regimen permits to obtain the two-year overall survival of 26%, nevertheless, the challenge
remains to improve clinical outcomes further.
Keywords: glioblastomachemotherapyradiotherapychemoradiotherapy