Vol 2, No 4 (2006)
Case report
Published online: 2006-09-26

open access

Page views 805
Article views/downloads 11058
Get Citation

Connect on Social Media

Connect on Social Media

Palliative chemotherapy with kapecytabine and gemcytabine in patients with advenced gallbladder cancer

Andrzej Kaiser, Marcin Wolski, Krzysztof Forgacz
Onkol. Prak. Klin 2006;2(4):174-180.

Abstract

Palliative chemotherapy was attempted in 4 patients with advanced gallbladder carcinoma (stage III or IV).The possibility of surgical treatment was excluded at all patients. Chemotherapy regimen GX included capecitabine (orally in the daily dose of 2500 mg/m2 day 1 to 14) and gemcitabine (intravenously in the dose 1000 mg/m2 day 1 and 8; repeated every 21 days). Normalization or significant reduction of initially elevated liver function tests (transaminases and bilirubin) and serum markers (CEA and CA 19.9) as well as symptom improvement or disapearance were found in all patients. These findings justify prospective study evaluating capecitabine- and gemcitabine-containing chemotherapy with regard of its impact on survival rates in patients with advanced gallbladder carcinoma.

Article available in PDF format

View PDF (Polish) Download PDF file