open access

Vol 3, No 3 (2007)
Case report
Published online: 2007-05-24
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Advanced rectal cancer

Ewa Anna Kosakowska, Dorota Nowakowska, Janusz Olędzki
Onkol. Prak. Klin 2007;3(3):150-154.

open access

Vol 3, No 3 (2007)
CASE REPORTS
Published online: 2007-05-24

Abstract

We present the case of a 42-year-old male patient treated for advanced rectal cancer. The treatment was initiated with capecitabine monotherapy with palliative intent, but in view of a dramatic progression during the fourth week of treatment cycle, chemotherapy regimen was changed to FOLFIRI (irinotecan, leucovorin, fluorouracil - 48 hours continuous infusion). By the end of the first treatment cycle a marked improvement was observed. Due to the aggressive course of disease we decided to change the chemotherapy regimen to IFL (irinotecan, leucovorin, fluorouracil - bolus) with bevacizumab. The patient's general condition improved markedly and all his symptoms resolved along with a partial objective response (80% regression of the lung lesions was observed on CT scan - partial remission). A spectacular response to chemotherapy regimen administered should be underlined.

Abstract

We present the case of a 42-year-old male patient treated for advanced rectal cancer. The treatment was initiated with capecitabine monotherapy with palliative intent, but in view of a dramatic progression during the fourth week of treatment cycle, chemotherapy regimen was changed to FOLFIRI (irinotecan, leucovorin, fluorouracil - 48 hours continuous infusion). By the end of the first treatment cycle a marked improvement was observed. Due to the aggressive course of disease we decided to change the chemotherapy regimen to IFL (irinotecan, leucovorin, fluorouracil - bolus) with bevacizumab. The patient's general condition improved markedly and all his symptoms resolved along with a partial objective response (80% regression of the lung lesions was observed on CT scan - partial remission). A spectacular response to chemotherapy regimen administered should be underlined.
Get Citation

Keywords

rectal cancer; paliative chemotherapy; irinotecan; bevacizumab

About this article
Title

Advanced rectal cancer

Journal

Oncology in Clinical Practice

Issue

Vol 3, No 3 (2007)

Article type

Case report

Pages

150-154

Published online

2007-05-24

Bibliographic record

Onkol. Prak. Klin 2007;3(3):150-154.

Keywords

rectal cancer
paliative chemotherapy
irinotecan
bevacizumab

Authors

Ewa Anna Kosakowska
Dorota Nowakowska
Janusz Olędzki

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