Apocrine adenocarcinoma of Moll glands - a case report and literature review

Abstract

A case of extremely rare apocrine adenonacarcinoma of Moll glands is described. A 58-year- old man complained of excessive lacrimation, exophtalmus and sight disorders of left eye. Clinical examination revealed his very good general condition and palpable tumor between left eye ball and a lower orbital rim. Magnetic resonance imaging (MRI) showed gross tumor volume extending to the whole orbit and paranasal sinuses. Exenteration of left orbit was performed. Histopatological examination confirmed low grade apocrine adenocarcinoma of Moll glands with nerves and vessels involvement. Adjuvant orbital and paranasal sinuses radiotherapy was performed with elective irradiation of cervical lymph nodes. There are no signs of recurrence or metastatic disease after 15 months of follow-up. Nonspecific symptoms of apocrine adenonacarcinoma of Moll glands need to be distinguished between more common benign diseases and other neoplasm of eyelids and orbit. The amount of literature data is insufficient to establish standards of treatment. Reporting cases of such rare malignancy seems to be highly indicated.