open access

Vol 4, No 3 (2008)
Case report
Published online: 2008-07-03
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Concomitant occurrence of Richter transformation and lung cancer in patient with chronic lymphotic leukemia

Krzysztof Adamowicz, Wanda Knopińska-Posłuszny, Andrzej Mital, Joanna Adamowicz, Jan Maciej Zaucha
Onkol. Prak. Klin 2008;4(3):110-113.

open access

Vol 4, No 3 (2008)
CASE REPORT
Published online: 2008-07-03

Abstract

Development of systemic symptoms such as losing weight, fever or local symptoms such as rapidly growing organomegaly in a patient with chronic lymphocytic leukemia (CLL) suggests transformation to high grade lymphoma known as Richter's syndrome. Similar symptoms can occur in case of second malignancy, which incidence in patients with CLL is 10–20% higher compared to normal population. Here we present a case of a 59-year-old patient who simultaneously developed transformation to Hodgkin's disease and non small cell lung cancer 2 years after CLL diagnosis. Clinical course, diagnostic and therapeutic difficulties in such case is discussed.

Abstract

Development of systemic symptoms such as losing weight, fever or local symptoms such as rapidly growing organomegaly in a patient with chronic lymphocytic leukemia (CLL) suggests transformation to high grade lymphoma known as Richter's syndrome. Similar symptoms can occur in case of second malignancy, which incidence in patients with CLL is 10–20% higher compared to normal population. Here we present a case of a 59-year-old patient who simultaneously developed transformation to Hodgkin's disease and non small cell lung cancer 2 years after CLL diagnosis. Clinical course, diagnostic and therapeutic difficulties in such case is discussed.
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Keywords

chronic lymphocytic leukemia; Richter' s syndrome; Hodgkin' s lymphoma; second malignancy

About this article
Title

Concomitant occurrence of Richter transformation and lung cancer in patient with chronic lymphotic leukemia

Journal

Oncology in Clinical Practice

Issue

Vol 4, No 3 (2008)

Article type

Case report

Pages

110-113

Published online

2008-07-03

Bibliographic record

Onkol. Prak. Klin 2008;4(3):110-113.

Keywords

chronic lymphocytic leukemia
Richter's syndrome
Hodgkin's lymphoma
second malignancy

Authors

Krzysztof Adamowicz
Wanda Knopińska-Posłuszny
Andrzej Mital
Joanna Adamowicz
Jan Maciej Zaucha

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