open access

Vol 4, No 6 (2008)
Review paper
Published online: 2008-12-16
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Opportunities of combined treatment in metastatic colorectal cancer

Janusz Kocik, Mateusz Ziarkiewicz, Anna Świeboda-Sadlej, Marzanna Staszewska-Skurczyńska, Hubert Heleniak, Ewa Żurawińska, Piyush Vyas
Onkol. Prak. Klin 2008;4(6):213-218.

open access

Vol 4, No 6 (2008)
REVIEW ARTICLES
Published online: 2008-12-16

Abstract

In majority of patients newly diagnosed colorectal cancer is advanced, in vast number of patients presents in metastatic phase. In last decade convenience of new, effective drugs improved expected survival in metastatic phase of disease. Clinical trials of last few years have shown that proficient combination of continuous, sequential systemic treatment with courageous metastases resection increases chance for long survival. In this article authors analyzed the newest reports from trials designed to answer the queries about indications to systemic and surgical treatment in palliative setting as well as intensity and sequence of combination of cytotoxic and targeted therapies. Owing to knowledge gained through these studies the aim of cure is possible instead of only delaying progression in late phase of the disease.

Abstract

In majority of patients newly diagnosed colorectal cancer is advanced, in vast number of patients presents in metastatic phase. In last decade convenience of new, effective drugs improved expected survival in metastatic phase of disease. Clinical trials of last few years have shown that proficient combination of continuous, sequential systemic treatment with courageous metastases resection increases chance for long survival. In this article authors analyzed the newest reports from trials designed to answer the queries about indications to systemic and surgical treatment in palliative setting as well as intensity and sequence of combination of cytotoxic and targeted therapies. Owing to knowledge gained through these studies the aim of cure is possible instead of only delaying progression in late phase of the disease.
Get Citation

Keywords

colorectal cancer; metastases; resection; chemotherapy; targeted therapy

About this article
Title

Opportunities of combined treatment in metastatic colorectal cancer

Journal

Oncology in Clinical Practice

Issue

Vol 4, No 6 (2008)

Article type

Review paper

Pages

213-218

Published online

2008-12-16

Bibliographic record

Onkol. Prak. Klin 2008;4(6):213-218.

Keywords

colorectal cancer
metastases
resection
chemotherapy
targeted therapy

Authors

Janusz Kocik
Mateusz Ziarkiewicz
Anna Świeboda-Sadlej
Marzanna Staszewska-Skurczyńska
Hubert Heleniak
Ewa Żurawińska
Piyush Vyas

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