Vol 5, No 1 (2009)
Case report
Published online: 2009-02-02
Giant condyloma acuminata of the perianal, scrotal and penile area with the focuses of squamous cell carcinoma - a case report
Onkol. Prak. Klin 2009;5(1):33-36.
Abstract
Condyloma acuminata (CA) called genital warts is caused by human papilloma virus (HPV). The Buschke-
Lovenstein tumor (BLT), a clinical variant of CA, is considered to be a premalignant stadium. Relatively rarely,
CA undergo malignant transformation into squamous cell carcinoma (SCC). There are many different treatment
modalities available for the CA, but standard management is still not established , probably due to small
number of treated patients. Traditionally surgical resection was the gold standard but there was the high rate
of local recurrences. Neither systemic therapy (chemotherapy, immunotherapy) nor radiotherapy delivered
as a single method of treatment brought expected results. This paper presents the case of a 51-years-old
patient with the SSC of the perianal, scrotal and penile area subsequent to CA. Patient was not qualified for
radical surgery due to local advance of disease and radiochemotherapy was applied. The treatment resulted
in objective disease remission, clinical improvement and almost total regression of pain. Short literature
review was included to this case presentation.
Keywords: condyloma acuminatasquamous cell carcinomaradiochemotherapy
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