open access

Vol 5, No 1 (2009)
Case report
Published online: 2009-02-02
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Giant condyloma acuminata of the perianal, scrotal and penile area with the focuses of squamous cell carcinoma - a case report

Grzegorz Słomian, Małgorzata Chrószcz
Onkol. Prak. Klin 2009;5(1):33-36.

open access

Vol 5, No 1 (2009)
CASE REPORTS
Published online: 2009-02-02

Abstract

Condyloma acuminata (CA) called genital warts is caused by human papilloma virus (HPV). The Buschke- Lovenstein tumor (BLT), a clinical variant of CA, is considered to be a premalignant stadium. Relatively rarely, CA undergo malignant transformation into squamous cell carcinoma (SCC). There are many different treatment modalities available for the CA, but standard management is still not established , probably due to small number of treated patients. Traditionally surgical resection was the gold standard but there was the high rate of local recurrences. Neither systemic therapy (chemotherapy, immunotherapy) nor radiotherapy delivered as a single method of treatment brought expected results. This paper presents the case of a 51-years-old patient with the SSC of the perianal, scrotal and penile area subsequent to CA. Patient was not qualified for radical surgery due to local advance of disease and radiochemotherapy was applied. The treatment resulted in objective disease remission, clinical improvement and almost total regression of pain. Short literature review was included to this case presentation.

Abstract

Condyloma acuminata (CA) called genital warts is caused by human papilloma virus (HPV). The Buschke- Lovenstein tumor (BLT), a clinical variant of CA, is considered to be a premalignant stadium. Relatively rarely, CA undergo malignant transformation into squamous cell carcinoma (SCC). There are many different treatment modalities available for the CA, but standard management is still not established , probably due to small number of treated patients. Traditionally surgical resection was the gold standard but there was the high rate of local recurrences. Neither systemic therapy (chemotherapy, immunotherapy) nor radiotherapy delivered as a single method of treatment brought expected results. This paper presents the case of a 51-years-old patient with the SSC of the perianal, scrotal and penile area subsequent to CA. Patient was not qualified for radical surgery due to local advance of disease and radiochemotherapy was applied. The treatment resulted in objective disease remission, clinical improvement and almost total regression of pain. Short literature review was included to this case presentation.
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Keywords

condyloma acuminata; squamous cell carcinoma; radiochemotherapy

About this article
Title

Giant condyloma acuminata of the perianal, scrotal and penile area with the focuses of squamous cell carcinoma - a case report

Journal

Oncology in Clinical Practice

Issue

Vol 5, No 1 (2009)

Article type

Case report

Pages

33-36

Published online

2009-02-02

Bibliographic record

Onkol. Prak. Klin 2009;5(1):33-36.

Keywords

condyloma acuminata
squamous cell carcinoma
radiochemotherapy

Authors

Grzegorz Słomian
Małgorzata Chrószcz

References (16)
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