Vol 5, No 3 (2009)
Review paper
Published online: 2009-05-15
Management of oncology patients with history of cardiovascular diseases
Onkol. Prak. Klin 2009;5(3):83-91.
Abstract
Cardiovascular diseases (CVDs) and cancers are the main causes of death, therefore oncological patient
often suffers from cardiologic disease. Intensive chemotherapy improves the prognosis, reduces mortality
and lengthens life of oncological patients but it is also connected with applying of potentially cardiotoxic
drugs. In this article, we presented the risk factors of CVDs and the methods of its individual estimation in
order to perform qualification and treatment monitoring in subjects at baseline increased risk of cardiac
disease. We described treatment of myocardial ischemia, hypertension and congestive heart failure in this
patients. On example of anthracyclines and trastuzumab the mechanisms of the cardiotoxicity of drugs
used in oncology, monitoring of potentially cardiotoxic treatment and strategies to reduce cardiovascular
toxicity were presented.
Keywords: cardiovascular diseasescancerchemotherapyrisk factorscardiotoxicity
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