open access

Vol 5, Supp. A (2009)
suplement
Published online: 2009-04-29
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Antiangiogenic treatment of primary cancers of central nervous system

Marek Z. Wojtukiewicz, Ewa Sierko, Mirosław Rybałtowski

open access

Vol 5, Supp. A (2009)
suplement
Published online: 2009-04-29

Abstract

High grade gliomas are among the most common primary brain tumors. They are highly vascularized structures and may serve as a perfect model to study the process of tumor angiogenesis and to investigate new anti-angiogenic therapies. This review focuses on the role of angiogenic factors in glioma development and presents new therapeutic strategies which interfere with angiogenesis.

Abstract

High grade gliomas are among the most common primary brain tumors. They are highly vascularized structures and may serve as a perfect model to study the process of tumor angiogenesis and to investigate new anti-angiogenic therapies. This review focuses on the role of angiogenic factors in glioma development and presents new therapeutic strategies which interfere with angiogenesis.
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Keywords

angiogenesis; malignant glioma; glioblastoma; VEGF; targeted therapy; tyrosine kinase inhibitors

About this article
Title

Antiangiogenic treatment of primary cancers of central nervous system

Journal

Oncology in Clinical Practice

Issue

Vol 5, Supp. A (2009)

Pages

48-55

Published online

2009-04-29

Keywords

angiogenesis
malignant glioma
glioblastoma
VEGF
targeted therapy
tyrosine kinase inhibitors

Authors

Marek Z. Wojtukiewicz
Ewa Sierko
Mirosław Rybałtowski

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