Vol 6, No 5 (2010)
Review paper
Published online: 2011-01-19
Direct EGFR inhibition imaging in tageted treatment in neoplastic diseases
Onkol. Prak. Klin 2010;6(5):278-282.
Abstract
Epidermal growth factor receptor (EGFR) targeted therapy is a novel pharmacological approach to a treatment
of neoplastic diseases in humans. In a clinical practice treatment results are currently monitored in
vivo using indirect (not targeted to EGFR) imaging strategies, like computed tomography, ultrasound or
classical magnetic resonance imaging. However, methods dedicated for direct EGFR imaging and based
on positron emission tomography are already at the preclinical stage of development. In the paper, most
important data related to direct EGFR expression imaging in neoplasms was reviewed.
Onkol. Prak. Klin. 2010; 6, 5: 278–282
Keywords:
EGFREGFimagingPETtargeted therapycancer disease
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