open access

Vol 6, Supp. A (2010)
suplement
Published online: 2010-11-22
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Posttreatment cardiotoxity in patient with lymphoma

Wojciech Jurczak, Tomasz Ogórka

open access

Vol 6, Supp. A (2010)
suplement
Published online: 2010-11-22

Abstract

Efficacy of anti-lymphoma therapy, prolonging significantly overall survival, allows us to observe late adverse effects of antineoplastic drugs. Cardiotoxicity of anthracyclins is dose dependent and increasing with time elapsed after therapy. It is more pronounced in patients with pre-existing heart disorders, treated with combined chemotherapy regimens or concomitant mediastinal radiotherapy. Cardiotoxic effects may be attenuated by using regimens with a low cumulative dose of anthracyclins, their liposomal formulations or cardioprotective substances.
Onkol. Prak. Klin. 2010; supl. A: A18–A24

Abstract

Efficacy of anti-lymphoma therapy, prolonging significantly overall survival, allows us to observe late adverse effects of antineoplastic drugs. Cardiotoxicity of anthracyclins is dose dependent and increasing with time elapsed after therapy. It is more pronounced in patients with pre-existing heart disorders, treated with combined chemotherapy regimens or concomitant mediastinal radiotherapy. Cardiotoxic effects may be attenuated by using regimens with a low cumulative dose of anthracyclins, their liposomal formulations or cardioprotective substances.
Onkol. Prak. Klin. 2010; supl. A: A18–A24
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Keywords

ardiotoxty; doxorubicin; lymphoma

About this article
Title

Posttreatment cardiotoxity in patient with lymphoma

Journal

Oncology in Clinical Practice

Issue

Vol 6, Supp. A (2010)

Pages

18-24

Published online

2010-11-22

Keywords

ardiotoxty
doxorubicin
lymphoma

Authors

Wojciech Jurczak
Tomasz Ogórka

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