Vol 7, No 2 (2011)
Review paper
Published online: 2011-06-22
Maintenance treatment of patients with follicular lymphoma
Onkol. Prak. Klin 2011;7(2):84-88.
Abstract
Follicular lymphoma (FL) is a relatively frequent malignant disease, comprising approximately 20% of
lymphoid malignancies. Clinically it is defined as an indolent disease. Despite the recent progress in
treatment of hematological tumors, FL still remains an incurable disease. In patients with progressive
disease, a standard of first line treatment are COP (cyclophosphamide, vincristine, prednizon) or CHOP
(cyclophosphamide, doksorubicine, vincristine, prednizon) regimens, administrated in combination with
anti-CD20 antigen antibody, rituximab (RIT). Most recently, the role of RIT maintenance in prolongation
of disease progression free survival and, potentially, overall survival of FL patients has been underlined.
Onkol. Prak. Klin. 2011; 7, 2: 84–88
Onkol. Prak. Klin. 2011; 7, 2: 84–88
Keywords: follicular lymphomaimmunochemotherapymaintenance treatment