Vol 7, No 3 (2011)
Case report
Published online: 2011-08-23

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Liposomal doxorubicin-induced cardiotoxicity — case report

Ewa Chmielowska, Mariusz Kwiatkowski
Onkol. Prak. Klin 2011;7(3):152-156.

Abstract

We report on a case of a female patient with relapsed metastatic bone disease from triple-negative breast cancer after primary radical treatment. In years 2002–2010 patient has received four lines of chemotherapy. After receiving 6th course of full-dose liposomal doxorubicin during fourth-line treatment patient has been diagnosed with acute cardiac failure with decreased left ventricular ejection fraction to value of 35%. Another ECHO examination after 2 months showed no significant improvement despite the applied treatment (LVEF 38%). Chemotherapy has been discontinued. Patient has died 4 months later because of cachexia and disease progression.
Presented case illustrates the difficulties associated with increasing risk of complications among patients treated with several lines of chemotherapy.
Onkol. Prak. Klin. 2011; 7, 3: 152–156

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