Anaplastic large cell lymphoma — three different entities

Abstract

Anaplastic large cell lymphoma (ALCL) is rare entity derived from T-lymphocytes. In the classification of World Health Organisation (WHO) ALCL is divided into cutaneous and two systemic types (ALK+ and ALK–), differring in terms of clinical features, genetic changes and partly histopathology and immunophenotype. Proper diagnosis is crucial and determines treatment. I present a case of 61-year-old woman with resistant to treatment systemic ALK-type of ALCL and briefly describe this disease entity.
Onkol. Prak. Klin. 2011; 7, 3: 146–151