open access

Vol 14, No 5 (2018)
Case report
Published online: 2019-02-15
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Tracheal cancer in a 25-year-old woman — diagnostic difficulties

Magdalena Zaborowska-Szmit, Aleksandra Piórek, Dariusz M Kowalski, Maciej Krzakowski
DOI: 10.5603/OCP.2018.0037
·
Oncol Clin Pract 2018;14(5):286-289.

open access

Vol 14, No 5 (2018)
CASE REPORT
Published online: 2019-02-15

Abstract

Tracheal cancers, in particular adenoid cystic carcinoma, are rare, hence the lack of unambiguous guidelines for diagnostic and therapeutic procedures. The article presents the case of a 25-year-old woman diagnosed at the stage of local advancement, after 2 years of treatment of misdiagnosed bronchial asthma. The patient underwent surgical treatment, which turned out to be non-radical microscopically. The decision to use postoperative radiotherapy was based on the estimated recurrence risk.

Abstract

Tracheal cancers, in particular adenoid cystic carcinoma, are rare, hence the lack of unambiguous guidelines for diagnostic and therapeutic procedures. The article presents the case of a 25-year-old woman diagnosed at the stage of local advancement, after 2 years of treatment of misdiagnosed bronchial asthma. The patient underwent surgical treatment, which turned out to be non-radical microscopically. The decision to use postoperative radiotherapy was based on the estimated recurrence risk.
Get Citation

Keywords

tracheal cancer; adenoid cystic carcinoma; postoperative radiotherapy; bronchial asthma

About this article
Title

Tracheal cancer in a 25-year-old woman — diagnostic difficulties

Journal

Oncology in Clinical Practice

Issue

Vol 14, No 5 (2018)

Article type

Case report

Pages

286-289

Published online

2019-02-15

DOI

10.5603/OCP.2018.0037

Bibliographic record

Oncol Clin Pract 2018;14(5):286-289.

Keywords

tracheal cancer
adenoid cystic carcinoma
postoperative radiotherapy
bronchial asthma

Authors

Magdalena Zaborowska-Szmit
Aleksandra Piórek
Dariusz M Kowalski
Maciej Krzakowski

References (18)
  1. Chang CY, Cheng SL, Chang SC. Adenoid cystic carcinoma of trachea treated with tumor curettage and adjuvant intensity modulated radiation therapy. South Med J. 2011; 104(1): 68–70.
  2. Regnard JF, Fourquier P, Levasseur P. Results and prognostic factors in resections of primary tracheal tumors: a multicenter retrospective study. The French Society of Cardiovascular Surgery. J Thorac Cardiovasc Surg. 1996; 111(4): 808–13; discussion 813.
  3. Yamamoto Y, Wistuba II, Kishimoto Y, et al. DNA analysis at p53 locus in adenoid cystic carcinoma: comparison of molecular study and p53 immunostaining. Pathol Int. 1998; 48(4): 273–280.
  4. Kim B. Palliative radiotherapy in a patient with pulmonary adenoid cystic carcinoma. Cancer Res Treat. 2007; 39(4): 185–188.
  5. Chargari C, Riet F, Mazevet M, et al. Complications of thoracic radiotherapy. Presse Med. 2013; 42(9 Pt 2): e342–e351.
  6. Maziak D, Todd T, Keshavjee S, et al. Adenoid cystic carcinoma of the airway: Thirty-two-year experience. The Journal of Thoracic and Cardiovascular Surgery. 1996; 112(6): 1522–1532.
  7. Honings J, Gaissert HA, Weinberg AC, et al. Prognostic value of pathologic characteristics and resection margins in tracheal adenoid cystic carcinoma. Eur J Cardiothorac Surg. 2010; 37(6): 1438–1444.
  8. Kanematsu T, Yohena T, Uehara T, et al. Treatment outcome of resected and nonresected primary adenoid cystic carcinoma of the lung. Ann Thorac Cardiovasc Surg. 2002; 8(2): 74–77.
  9. Webb BD, Walsh GL, Roberts DB, et al. Primary tracheal malignant neoplasms: the University of Texas MD Anderson Cancer Center experience. J Am Coll Surg. 2006; 202(2): 237–246.
  10. Shimizu J, Oda M, Matsumoto I, et al. Clinicopathological study of surgically treated cases of tracheobronchial adenoid cystic carcinoma. Gen Thorac Cardiovasc Surg. 2010; 58(2): 82–86.
  11. Junker K. Pathology of tracheal tumors. Thorac Surg Clin. 2014; 24(1): 7–11.
  12. Macchiarini P. Primary tracheal tumours. Lancet Oncol. 2006; 7(1): 83–91.
  13. Samant S, van den Brekel MW, Kies MS, et al. Concurrent chemoradiation for adenoid cystic carcinoma of the head and neck. Head Neck. 2012; 34(9): 1263–1268.
  14. Mornex F, Coquard R, Danhier S, et al. Role of radiation therapy in the treatment of primary tracheal carcinoma. Int J Radiat Oncol Biol Phys. 1998; 41(2): 299–305.
  15. Napieralska A, Miszczyk L, Blamek S. Tracheal cancer - treatment results, prognostic factors and incidence of other neoplasms. Radiol Oncol. 2016; 50(4): 409–417.
  16. Marks LB, Yorke ED, Jackson A, et al. Use of normal tissue complication probability models in the clinic. Int J Radiat Oncol Biol Phys. 2010; 76(3 Suppl): S10–S19.
  17. Papaspyrou G, Hoch S, Rinaldo A, et al. Chemotherapy and targeted therapy in adenoid cystic carcinoma of the head and neck: a review. Head Neck. 2011; 33(6): 905–911.
  18. Laurie SA, Ho AL, Fury MG, et al. Systemic therapy in the management of metastatic or locally recurrent adenoid cystic carcinoma of the salivary glands: a systematic review. Lancet Oncol. 2011; 12(8): 815–824.

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