A rare metastasis to the vitreous from primary breast lymphoma
Abstract
Primary breast lymphoma (PBL) is a rare neoplasm that appears exclusively in the breast at the time of diagnosis. Isolated lymphoma metastasis to the vitreous is exceedingly rare and may pose a great diagnostic challenge. Herein, we describe a case of a 75-year-old Taiwanese female with initial presentation of PBL of B-cell origin, which remitted after six cycles of CHOP chemotherapy. Two years after the achievement of a complete response, she was noted to develop a progressive blurring due to vitreous floaters in the left eye. Histopathological features of vitrectomy specimens and clinical implications were consistent with vitreous spread of B-cell lymphoma. This presentation aims to improve knowledge on these extranodal lymphomas and to avoid unnecessary delay in the treatment of patients presenting with similar scenarios.
Keywords: breast lymphomadiffuse large B-cellPET/CTvitreous metastasis
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