open access

Vol 12, No 3 (2016)
Case report
Published online: 2016-08-31
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A rare metastasis to the vitreous from primary breast lymphoma

Rong-Hsin Yang, Tse-Hao Lee, Yum-Kung Chu
Oncol Clin Pract 2016;12(3):108-111.

open access

Vol 12, No 3 (2016)
CASE REPORT
Published online: 2016-08-31

Abstract

Primary breast lymphoma (PBL) is a rare neoplasm that appears exclusively in the breast at the time of diagnosis. Isolated lymphoma metastasis to the vitreous is exceedingly rare and may pose a great diagnostic challenge. Herein, we describe a case of a 75-year-old Taiwanese female with initial presentation of PBL of B-cell origin, which remitted after six cycles of CHOP chemotherapy. Two years after the achievement of a complete response, she was noted to develop a progressive blurring due to vitreous floaters in the left eye. Histopathological features of vitrectomy specimens and clinical implications were consistent with vitreous spread of B-cell lymphoma. This presentation aims to improve knowledge on these extranodal lymphomas and to avoid unnecessary delay in the treatment of patients presenting with similar scenarios.

Abstract

Primary breast lymphoma (PBL) is a rare neoplasm that appears exclusively in the breast at the time of diagnosis. Isolated lymphoma metastasis to the vitreous is exceedingly rare and may pose a great diagnostic challenge. Herein, we describe a case of a 75-year-old Taiwanese female with initial presentation of PBL of B-cell origin, which remitted after six cycles of CHOP chemotherapy. Two years after the achievement of a complete response, she was noted to develop a progressive blurring due to vitreous floaters in the left eye. Histopathological features of vitrectomy specimens and clinical implications were consistent with vitreous spread of B-cell lymphoma. This presentation aims to improve knowledge on these extranodal lymphomas and to avoid unnecessary delay in the treatment of patients presenting with similar scenarios.

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Keywords

breast lymphoma, diffuse large B-cell, PET/CT, vitreous metastasis

About this article
Title

A rare metastasis to the vitreous from primary breast lymphoma

Journal

Oncology in Clinical Practice

Issue

Vol 12, No 3 (2016)

Article type

Case report

Pages

108-111

Published online

2016-08-31

Bibliographic record

Oncol Clin Pract 2016;12(3):108-111.

Keywords

breast lymphoma
diffuse large B-cell
PET/CT
vitreous metastasis

Authors

Rong-Hsin Yang
Tse-Hao Lee
Yum-Kung Chu

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