open access

Vol 11, No 5 (2015)
Review paper
Published online: 2016-02-17
Get Citation

Palliative systemic treatment of bladder cancer

Piotr Wysocki
Oncol Clin Pract 2015;11(5):263-266.

open access

Vol 11, No 5 (2015)
REVIEW ARTICLES
Published online: 2016-02-17

Abstract

The systemic treatment of the bladder cancer is challenging. It is so due to moderate efficacy of chemotherapy and because of the restrictions secondary to the patient’s general performance status as well as an inadequate organ function (mainly renal function). The standards of the first line systemic treatment are established. The chemotherapy regimens containing platine derivates (preferably cisplatine) such as PG or MVAC are administered routinely. However such standard regarding the second line of systemic treatment is not defined. this reflects the lack of reliable scientific evidence supporting the chemotherapy use at this stage of the disease. Among several drugs being considered as the second line chemotherapy it is only vinflunine that proved its activity in phase III clinical trial and compared to the best supportive care improves prognosis and positively influence the quality of life.

Abstract

The systemic treatment of the bladder cancer is challenging. It is so due to moderate efficacy of chemotherapy and because of the restrictions secondary to the patient’s general performance status as well as an inadequate organ function (mainly renal function). The standards of the first line systemic treatment are established. The chemotherapy regimens containing platine derivates (preferably cisplatine) such as PG or MVAC are administered routinely. However such standard regarding the second line of systemic treatment is not defined. this reflects the lack of reliable scientific evidence supporting the chemotherapy use at this stage of the disease. Among several drugs being considered as the second line chemotherapy it is only vinflunine that proved its activity in phase III clinical trial and compared to the best supportive care improves prognosis and positively influence the quality of life.

Get Citation

Keywords

bladder cancer, chemotherapy, palliative treatment

About this article
Title

Palliative systemic treatment of bladder cancer

Journal

Oncology in Clinical Practice

Issue

Vol 11, No 5 (2015)

Article type

Review paper

Pages

263-266

Published online

2016-02-17

Bibliographic record

Oncol Clin Pract 2015;11(5):263-266.

Keywords

bladder cancer
chemotherapy
palliative treatment

Authors

Piotr Wysocki

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl