open access

Vol 11, No 3 (2015)
Review paper
Published online: 2015-07-29
Get Citation

Does coeliac disease predispose to the development of cancer?

Marek K. Kowalski, Anita Gąsiorowska
Onkol. Prak. Klin 2015;11(3):140-148.

open access

Vol 11, No 3 (2015)
REVIEW ARTICLES
Published online: 2015-07-29

Abstract

Celiac disease (CD) is an autoimmune response induced by gliadin and glutelin derivatives in genetically predisposed individuals. There is currently an increase in the frequency of CD diagnosis in most highly developed countries. Because of the course of the disease associated with chronic inflammation within the wall of the small intestine, it is assumed the idea that celiac disease predisposes to the development of cancer. Until now several studies was performed to evaluate the risk of developing malignant disease among patients with celiac disease. The results of retrospective studies are not conclusive, but some of them indicates an increased risk of developing certain types of cancer among patients with celiac disease. The purpose of this paper is to present the latest research on the issue of the development of cancer among patients with celiac disease. We would also like to draw attention to the risks which may have a significant impact on the development of cancer in this group of patients.

Abstract

Celiac disease (CD) is an autoimmune response induced by gliadin and glutelin derivatives in genetically predisposed individuals. There is currently an increase in the frequency of CD diagnosis in most highly developed countries. Because of the course of the disease associated with chronic inflammation within the wall of the small intestine, it is assumed the idea that celiac disease predisposes to the development of cancer. Until now several studies was performed to evaluate the risk of developing malignant disease among patients with celiac disease. The results of retrospective studies are not conclusive, but some of them indicates an increased risk of developing certain types of cancer among patients with celiac disease. The purpose of this paper is to present the latest research on the issue of the development of cancer among patients with celiac disease. We would also like to draw attention to the risks which may have a significant impact on the development of cancer in this group of patients.

Get Citation

Keywords

coeliac disease, malignancies, lymphoma, cancer, small intestine

About this article
Title

Does coeliac disease predispose to the development of cancer?

Journal

Oncology in Clinical Practice

Issue

Vol 11, No 3 (2015)

Article type

Review paper

Pages

140-148

Published online

2015-07-29

Bibliographic record

Onkol. Prak. Klin 2015;11(3):140-148.

Keywords

coeliac disease
malignancies
lymphoma
cancer
small intestine

Authors

Marek K. Kowalski
Anita Gąsiorowska

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl