open access

Vol 11, No 1 (2015)
Onkologia na świecie
Published online: 2015-03-12
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Prognosis and biology in esthesioneuroblastoma: the emerging role of Hyams grading system

Rami E. Saade, Ehab Y. Hanna, Diana Bell
Onkol. Prak. Klin 2015;11(1):53-59.

open access

Vol 11, No 1 (2015)
Onkologia na świecie
Published online: 2015-03-12

Abstract

Esthesioneuroblastoma is a sinonasal tumor with distinct clinicopathologic features, multiple facets, and a spectrum of behavior. Characterization of this disease is challenging, and clinically, several staging systems have been used with no consensus on a single scheme. Recently, the Hyams histological grading system has emerged as a promising prognostication tool that offers an added value to stage. This review addresses prognosis and biology in esthesioneuroblastoma. More specifically, we sought to present a critical appraisal on the value of each of these stratification systems, stage vs. grade, in identifying risk groups and guiding management.

Abstract

Esthesioneuroblastoma is a sinonasal tumor with distinct clinicopathologic features, multiple facets, and a spectrum of behavior. Characterization of this disease is challenging, and clinically, several staging systems have been used with no consensus on a single scheme. Recently, the Hyams histological grading system has emerged as a promising prognostication tool that offers an added value to stage. This review addresses prognosis and biology in esthesioneuroblastoma. More specifically, we sought to present a critical appraisal on the value of each of these stratification systems, stage vs. grade, in identifying risk groups and guiding management.

Get Citation

Keywords

esthesioneuroblastoma, olfactory neuroblastoma, Hyams, Kadish, Morita, stage, grade, prognosis, outcome

About this article
Title

Prognosis and biology in esthesioneuroblastoma: the emerging role of Hyams grading system

Journal

Oncology in Clinical Practice

Issue

Vol 11, No 1 (2015)

Pages

53-59

Published online

2015-03-12

Bibliographic record

Onkol. Prak. Klin 2015;11(1):53-59.

Keywords

esthesioneuroblastoma
olfactory neuroblastoma
Hyams
Kadish
Morita
stage
grade
prognosis
outcome

Authors

Rami E. Saade
Ehab Y. Hanna
Diana Bell

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