Proceedings in penile cancer

Abstract

Carcinoma of the penis is a rare cancer, but due to therapeutic difficulties represents a significant health problem in many countries. The most common form is squamous cell histology. The occurrence is often associated with the presence of the foreskin and inadequate hygiene. Penile carcinoma manifests as a flat or ulcerative, red or gray-white spots around the foreskin or penile glans. Treatment of choice is wide surgical excision or partial/total penectomy. Prophylactic excision of inguinal lymph nodes is the subject of controversy. Radiation therapy may provide local control, particularly for small primary lesions. The incidence of relapse after radiation treatment reaches 30%, thus still is the standard surgical treatment, in particular for large changes. Chemotherapy may be used as adjuvant or palliative treatment.