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Vol 9, No 5 (2013)
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Published online: 2013-12-03
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Positron emission tomography in oncology with use of radiotracers alternative to 18F-fluorodeoxyglucose

Edyta Szurowska, Jacek Teodorczyk, Katarzyna Dziadziuszko, Joanna Pieńkowska, Grzegorz Romanowicz, Piotr Lass
Onkol. Prak. Klin 2013;9(5):197-199.

open access

Vol 9, No 5 (2013)
REVIEW ARTICLES
Published online: 2013-12-03

Abstract

The objective of the article is to present of clinically most relevant oncological applications of positron emission tomography with use of radiotracers alternative to 18F-fluorodeoxyglucose. These studies are applied with increasing frequency also in the case of lesions demonstrating low, insufficient for imaging uptake of glucose-basedradiotracer. 18F-fluorodeoxyglucose positron emission tomography allows assessment of metabolic rate in many frequently occurring neoplasms. In case of low-level or highly variable 18F-fluorodeoxyglucose uptake alternative radiotracers must be used. Clinically most relevant are isotopically labeled amino acids, nucleic acids components, cell membrane components or Krebs cycle substrates. Radiotracers alternative to 18F-fluorodeoxyglucose enable also evaluation of functional parameters other than metabolic such as e.g. receptor density or hypoxia level.

Abstract

The objective of the article is to present of clinically most relevant oncological applications of positron emission tomography with use of radiotracers alternative to 18F-fluorodeoxyglucose. These studies are applied with increasing frequency also in the case of lesions demonstrating low, insufficient for imaging uptake of glucose-basedradiotracer. 18F-fluorodeoxyglucose positron emission tomography allows assessment of metabolic rate in many frequently occurring neoplasms. In case of low-level or highly variable 18F-fluorodeoxyglucose uptake alternative radiotracers must be used. Clinically most relevant are isotopically labeled amino acids, nucleic acids components, cell membrane components or Krebs cycle substrates. Radiotracers alternative to 18F-fluorodeoxyglucose enable also evaluation of functional parameters other than metabolic such as e.g. receptor density or hypoxia level.
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Keywords

PET, nuclear medicine, oncology, alternative radiotracers

About this article
Title

Positron emission tomography in oncology with use of radiotracers alternative to 18F-fluorodeoxyglucose

Journal

Oncology in Clinical Practice

Issue

Vol 9, No 5 (2013)

Pages

197-199

Published online

2013-12-03

Bibliographic record

Onkol. Prak. Klin 2013;9(5):197-199.

Keywords

PET
nuclear medicine
oncology
alternative radiotracers

Authors

Edyta Szurowska
Jacek Teodorczyk
Katarzyna Dziadziuszko
Joanna Pieńkowska
Grzegorz Romanowicz
Piotr Lass

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